Antibiotics

[Beverley Ann Johnson]

Can taking cefadroxil for infection make me feel like I have gluten stomach issues without the vomiting?

 

[knitty kitty]

Yes, you should report your symptoms to your doctor.

Your antibiotic is a sulfa drug.  Some Celiacs like me develop a Hypersensitivity reaction to sulfa drugs.  GI upsets, agitation,  difficulty breathing, and anaphylaxis are symptoms to look out for.  

Antibiotics also break thiamine down which can lead to an insufficiency of Thiamine.  

Antibiotics can also destroy good bacteria in the gastrointestinal tract.  

Thiamine supplementation has been shown to have antibacterial properties.  

Hope you feel better soon.

Happy Thanksgiving!

[Scott Adams]

I agree, and eating plain yogurt may help with stomach issues caused by antibiotics. 

[Beverley Ann Johnson]

Update, also had BPPV was rushed to ER on the 16th on December, verified my heart but was good. Let's say it has been horrible and the dizziness is going away gradually with massage therapy and mostly fasting.

I was so dizzy it followed a bout of vomiting and now have swollen glands neck and under chin.  Could this be gluten related?  My stomach and intestines are off so now have to take pantoprazole;  it also could be IBS flare.

Any input would be appreciated, Happy holidays to all.

 

 

 

[knitty kitty]

Happy Holidays, @Beverley Ann Johnson,

Sorry to hear about your trip to the ER.  Were you having tachycardia?  How long have you been vomiting?  Just that day or weeks?  Were you glutened?  

What are you currently eating?  How long have you been "mostly fasting"?   Are you taking any nutritional supplements, vitamins and minerals? 

Yes, the lymph nodes can swell.  Lymph nodes contain cells that make antibodies.  My lymph nodes were always swollen before diagnosis, but they are very small now.  Yes, mine do swell up after after being glutened or if I ever caught a cold.  But I have not caught a cold since I started high dose Thiamine.    

Thiamine helps the immune system fight infections.  Thiamine is needed to produce antibodies. Antibiotics like you were prescribed can cause thiamine deficiency disorders.  

Thiamine deficiency disorders have symptoms like nausea, vomiting, and gastrointestinal problems.  Dizziness and tachycardia are also symptoms.  I had all of these symptoms and more as my deficiency worsened.  I had been prescribed a PPI and anti-nausea pills.  Didn't work well.  PPIs cause further inflammation in the small intestine and prevent the absorption of vitamins and minerals.  My existing vitamin deficiencies from CeD just got worse.  My doctors were clueless. Heavy sigh.

Having studied Microbiology and Nutrition at university, I understood how cells inside our bodies require essential amino acids to function.  These essential amines are "vital amines" or vitamins.  Too simple, right?  But the pharmaceuticals weren't making me feel better.  Desperately grasping at straws, I started taking high doses of Thiamine and a B Complex supplement with all eight essential B vitamins, and magnesium.  

I started taking 500 mg  Thiamine Hydrochloride.  I had improvement of my symptoms within an hour!  It was truly amazing!

I continued taking 500 mg Thiamine Hydrochloride three times a day.  My symptoms continued to improve.  I found Allithiamine, a form of Thiamine called Tetrahydrofurfuryl Disulfide (TTFD) which helps immensely with resolving the dizziness, hearing loss, and brain fog.  I also took  Benfotiamine, a form of Thiamine shown to promote intestinal healing.  TTFD and Benfotiamine are forms of Thiamine that can get into cells easily, so a lower dose can be taken.  I had to make a guinea pig of myself, and, by trial and error, find what combination worked best for me.  

The World Health Organization says the best way to diagnose a thiamine deficiency is to take Thiamine for several days and look for improvement.  

Thiamine is safe and nontoxic in high doses.  Thiamine is water soluble meaning if you don't need it, you pee it out easily. 

Eat something sugary (candy or rice) if you haven't been eating.  Thiamine turns glucose in the blood into energy and blood glucose levels can drop. 

I invite you to be a guinea pig and try Thiamine.  Just to rule it out.  No harm, no foul.  

Hope this helps.  Keep us posted on your progress!

References:

 

....Restrictive diet in a patient with irritable bowel syndrome leading to Wernicke encephalopathy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056557/

....Hyperemesis-induced Wernicke-Korsakoff Syndrome due to Hypergastrinemia during Long-term Treatment with Proton Pump Inhibitors

https://pubmed.ncbi.nlm.nih.gov/32669503/

....Vertigo-Associated Vomiting: Acute Presentation of Thiamine Deficiency in Intestinal Failure

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158385/

....Vestibular Dysfunction in Wernicke’s Encephalopathy: Predominant Impairment of the Horizontal Semicircular Canals

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857915/

....Vestibular signs of thiamine deficiency during the early phase of suspected Wernicke encephalopathy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082353/

....Thiamine deficiency disorders: a clinical perspective

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451766/

....Hiding in Plain Sight: Modern Thiamine Deficiency

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533683/

[Beverley Ann Johnson]

Thanks for the information. I vomited once after the epley treatment but felt sick all the time.  The vertigo was bad and I still feel off but now have constipation and gas, every muscle and nerve wants to burp.

What about milk magnesium in liquid form could this help?  Or probiotics? I feel like I have stomach yeast right now.  

Thanks for your help

 

[knitty kitty]

Milk of magnesium is not absorbed well.  Instead it pulls water into the digestive system which relieves constipation temporarily.  

Magnesium Glycinate is absorbed better and with Thiamine helps muscles in the digestive system function properly.  Constipation is a symptom of Thiamine deficiency.

You may have Candida overgrowth or SIBO.  These happen frequently in CeD and while there's a thiamine deficiency.  Thiamine helps keep intestinal bacteria and yeasts in check.  SIBO bacteria and Candida can cause Thiamine deficiency because these organisms can eat up your nutrients like Thiamine before you have a chance to absorb it.  

SIBO can occur if you consume excess carbohydrates and have low stomach acid which leaves carbohydrates undigested for the SIBO bacteria to feed on.  Low stomach acid is common in Niacin and Thiamine deficiencies.

When this happened to me, I started following the Autoimmune Protocol Diet, a Paleo diet that removes sugars and most carbohydrates from the diet.  If you change your diet, you change your microbiome.  If you don't feed the SIBO bacteria the sugars and carbs, they starve and die off, giving the beneficial bacteria a chance to repopulate.  Three weeks on the AIP Paleo diet and I felt so much better, the gas, bloating and alternating diarrhea and constipation were no longer a problem.   

Be sure to supplement with a B Complex, magnesium, Vitamin D, and high dose Thiamine.  Thiamine is instrumental in regulating the intestinal bacteria and SIBO.  The gluten free diet can be deficient in the essential B vitamins.  Celiac Disease causes vitamin deficiencies due to malabsorption.  By supplementing with vitamins, you give your body a better opportunity to absorb vitamins and minerals needed for healing and feeling better.

Keep us posted on your progress!

References:

SIBO, IBS, and Constipation: Unrecognized Thiamine Deficiency?

https://www.hormonesmatter.com/sibo-ibs-constipation-thiamine-deficiency/

...The Autoimmune Protocol Diet Modifies Intestinal RNA Expression in Inflammatory Bowel Disease

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147823/

....Dietary Vitamin B1 Intake Influences Gut Microbial Community and the Consequent Production of Short-Chain Fatty Acids

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147846/

....Hiding in Plain Sight: Modern Thiamine Deficiency

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533683/

....Thiamine deficiency disorders: a clinical perspective

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451766/

Edited December 31, 2023 by knitty kitty
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