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Are these findings consistent with someone who has celiac disease?

Kelle91
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Kelle91 Newbie
Kelle91
Posted

 

The Z-line was irregular. Biopsies were taken with a cold forceps for histology.

Patchy mildly erythematous mucosa without bleeding was found in the gastric antrum. Biopsies were taken with a cold forceps for histology.

Diffuse granular mucosa was found in the first portion of the duodenum. Biopsies were taken with a cold forceps for histology.

Patchy mildly congested mucosa without active bleeding and with no stigmata of bleeding was found in the second portion of the duodenum. Biopsies were taken with a cold forceps for histology. 

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Scott Adams Grand Master
Scott Adams
Posted

Of course it's best to get the findings directly from your doctor, as I'm not a doctor, but the findings described in your endoscopy report could be consistent with celiac disease, but they are not definitive without the results of the biopsies. Here's how each finding relates to celiac disease:

Irregular Z-line: This finding is related to the esophagus and can be associated with conditions like gastroesophageal reflux disease (GERD), but it's not directly indicative of celiac disease.

Patchy mildly erythematous mucosa in the gastric antrum: This suggests mild inflammation in the stomach. While it can be seen in various conditions, it is not specific to celiac disease.

Diffuse granular mucosa in the first portion of the duodenum: This finding can be suggestive of celiac disease. The granular appearance is often due to villous atrophy and mucosal changes typical in celiac disease.

Patchy mildly congested mucosa in the second portion of the duodenum: This could also be consistent with celiac disease, which often affects the mucosa of the duodenum. 

In celiac disease, the most telling findings come from the duodenal biopsies. If the biopsies show villous atrophy, crypt hyperplasia, and increased intraepithelial lymphocytes, this would be consistent with celiac disease.

Therefore, while some of the endoscopic findings could be consistent with celiac disease, the definitive diagnosis relies on histological examination of the biopsies. You should wait for the biopsy results and discuss them with your healthcare provider to get a clear diagnosis.

Kelle91 Newbie
Kelle91
Posted
  • Author

Thank you so much, Scott. Your answer was incredibly helpful. Here are the biopsy results. I still haven’t gotten a call from the doctor’s office. 
 

D2 BIOPSIES:

Duodenal mucosa within normal limits.

B. D1 BIOPSIES:

Duodenal mucosa with foveolar metaplasia.

C. GASTRIC ANTRUM BIOPSIES:

Antral mucosa with mild chronic inactive gastritis.

No Helicobacter pylori seen on H&E stain.

D. GE JUNCTION BIOPSIES:

Cardia-type mucosa with chronic inflammation.

On 5/23/2024 at 2:36 PM, Scott Adams said:

Of course it's best to get the findings directly from your doctor, as I'm not a doctor, but the findings described in your endoscopy report could be consistent with celiac disease, but they are not definitive without the results of the biopsies. Here's how each finding relates to celiac disease:

Irregular Z-line: This finding is related to the esophagus and can be associated with conditions like gastroesophageal reflux disease (GERD), but it's not directly indicative of celiac disease.

Patchy mildly erythematous mucosa in the gastric antrum: This suggests mild inflammation in the stomach. While it can be seen in various conditions, it is not specific to celiac disease.

Diffuse granular mucosa in the first portion of the duodenum: This finding can be suggestive of celiac disease. The granular appearance is often due to villous atrophy and mucosal changes typical in celiac disease.

Patchy mildly congested mucosa in the second portion of the duodenum: This could also be consistent with celiac disease, which often affects the mucosa of the duodenum. 

In celiac disease, the most telling findings come from the duodenal biopsies. If the biopsies show villous atrophy, crypt hyperplasia, and increased intraepithelial lymphocytes, this would be consistent with celiac disease.

Therefore, while some of the endoscopic findings could be consistent with celiac disease, the definitive diagnosis relies on histological examination of the biopsies. You should wait for the biopsy results and discuss them with your healthcare provider to get a clear diagnosis.

No intestinal metaplasia identified.

Scott Adams Grand Master
Scott Adams
Posted

Did you get a blood panel done for celiac disease? If so, what were the results?

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