Help with results

[eekunique]

 

IgA 0.51 (range 0.34 - 3.05 g/L)

So while in range - it's quite low.

TTG 11.00 (range 0 - 20 U/m) 

TTG has been above range before (but only just) so carried on eating normally and this was test 6 months later. 

Lab wouldn't test EMA because TTG was normal which I find annoying as he's had positive EMA before. 

Dr says all normal so good news not coeliac. 

Would you consider this normal too. I just can't wrap my head around the fact that there are antibodies there - why would the body make antibodies against  something unless there was an autoimmune issue. 

Also it's for my son who's only 8 so would need general anesthetic for an endoscopy so we're not going to put him through that and Dr wouldn't agree it anyway. 

[eekunique]

😬

[Scott Adams]

For children the DGP-IgA and DGP-IgG (Deamidated Gliadin Peptide) should always be done, as their immune systems are not fully developed and the tTG-IgA doesn't always work. Given that he had what you describe as weak positive results, he could have celiac disease. 

This article might be helpful. It breaks down each type of test, and what a positive results means in terms of the probability that you might have celiac disease. 

 

 

A positive EMA test, according to the article:
 

Quote

The sensitivity of a test refers to its ability to correctly identify individuals with the condition. For the EMA-IgA blood test, the sensitivity is generally very high, ranging from 90% to 98%. This means that the test can accurately detect celiac disease in a significant percentage of people who have the condition.

The specificity of a test refers to its ability to correctly identify individuals without the condition. For the EMA-IgA blood test, the specificity is also high, typically around 95% to 100%. This indicates that the test can effectively rule out celiac disease in individuals who do not have the condition.