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How Long To Eat Gluten Before Biopsy?


mat4mel

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mat4mel Apprentice

Long story, but my 29 month old had positive antigliadin IgG and IgA back in April, started gluten free/dairy free diet in MAy, have seen some improvement but not completely and she is still not gaining much weight. I think maybe we should do the biopsy recommended by my ped GI dr and he is telling me that as soon as she starts showing symptoms after going on a gluten containing diet (even if it's just a week), then to do the biopsy.. but I'm not sure if that is long enough? Does anybody know?

I am going nuts. I am also due with another baby in 4 weeks and don't know if I should start gluten now or wait until after baby is born.

Mel


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celiac3270 Collaborator

Celiacs have internal symptoms at the slightest crumb of gluten....and some have external symptoms with one crumb, as well. Most doctors would recommend at least a month, usually 2-3 months of gluten. 2 months would probably be fine. Of course, all this depends on how much gluten your daughter has daily. Two meals for two months would do it.

erica Rookie

Hi, I was told to go back on gluten for a preiod of three months by Dr. Green of the Celiac Disease Center in NYC. It's been 2 months and I feel horrible but I have been told that even if I have started feeling symptoms, it may still not be enough time to see anything via endoscopy. 3 months is a safe bet

flagbabyds Collaborator

The person doing Celiac REseasrch at stanford ca, said 4 weeks to 3 months, 4 weeks if you eat only gluten 3 months if you eat 2 meals a day.

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    • knitty kitty
      So you're saying that you think you should have severe intestinal damage since you've had the symptoms so long?   DGP IgG antibodies are produced in response to a partial gluten molecule.  This is different than what tissue transglutaminase antibodies are  produced in response to.   TTg IgA antibodies are produced in the intestines in response to gluten.  The tTg IgA antibodies attack our own cells because a structural component in our cell membranes resembles a part of gluten.  There's a correlation between the level of intestinal damage with the level of tTg antibodies produced.  You are not producing a high number of tTg IgA antibodies, so your level of tissue damage in your intestines is not very bad.  Be thankful.   There may be reasons why you are not producing a high quantity of tTg IgA antibodies.  Consuming ten grams or more of gluten a day for two weeks to two months before blood tests are done is required to get sufficient antibody production and damage to the intestines.  Some undiagnosed people tend to subconsciously avoid lots of gluten.  Cookies and cakes do not contain as much gluten as artisan breads and thick chewy pizza crust.  Anemia, diabetes and thiamine deficiency can affect IgA antibody production as well.   Do you carry genes for Celiac?  They frequently go along with EDS.
    • rei.b
      I was tested for celiac at the same time, so I wasn't taking naltrexone yet. I say that, because I don't. The endoscopy showed some mild inflammation but was inconclusive as to celiac disease. They took several biopsies and that's all that was shown. I was not given a Marsh score.
    • knitty kitty
      Food and environmental allergies involve IgE antibodies.  IgE antibodies provoke histamine release from mast cells.   Celiac disease is not always visible to the naked eye during endoscopy.  Much of the damage is microscopic and patchy or out of reach of the scope.  Did they take any biopsies of your small intestine for a pathologist to examine?  Were you given a Marsh score? Why do you say you "don't have intestinal damage to correlate with lifelong undiagnosed celiac disease"?   Just curious.  
    • rei.b
      I was tested for food allergies and environmental allergies about 7 months before I started taking Naltrexone, so I don't think that is the cause for me, but that's interesting!  The main thing with the celiac thing that is throwing me off is these symptoms are lifelong, but I don't have intestinal damage to correlate with lifelong undiagnosed celiac disease.
    • trents
      Welcome to the forum, @Kara S! Warrior bread is a grain free bread product. Google it. There are commercial mixes available, I believe, Youtube videos and many recipes. 
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