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Negative Iga Anti Ttg But Positive Biopsy....

kasia

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kasia Rookie
kasia
Posted

Hi

I was diagnosed by biopsy on 17th October (carried out by private medical insurance on 4th October). I had an Iga Anti TTg blood test on the 10th October (blood test carried out by National Health Sevice in England) & it came back negative.

If I had not had private medical insurance, the NHS would certainly not have sent me for a biopsy in an NHS hospital with a negative result, so I would still be having all the symptoms & feeling dreadful.

Is it unusual to get negative blood & positive biopsy? Thank goodness for my insurance!

BTW been on the diet for 6ish weeks now & feeling great.

Thanks for all your help

Kate

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nikki-uk Enthusiast
nikki-uk
Posted

Hi Kate - I'm in the UK also.

My husband had a negative tTg but a positive biopsy (all courtesy of the NHS!)

A small number of coeliacs have Seronegative celiac disease (I think around 3%)

My hubby was in hospital for a month whilst they tried to find out what was wrong - they knew the bloods come back negative for celiac disease but went ahead with an endoscopy and colonoscopy as they were looking for other conditions.

Glad you're feeling better on a gluten-free diet!! :)

chrissy Collaborator
chrissy
Posted

it is not common---but it does happen---especially if you are IgA deficient and a total IgA serum was not done as part of the blood work.

kasia Rookie
kasia
Posted
  • Author

Hi Nikki & Christine,

Thanks for your replies - I was rather confused about why my blood was negative & a bit concerned about what the possible outcomes would have been with only the blood test.

The diet is great though (although I am beginning to really miss real lager - roll on a good gluten-free substitute!)

Kate

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