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MissCici

Negative Blood Work, But Positive Biopsy?

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My blood test showed negative for Celiac in late May, but since I have many of the symptoms, by doc is going to do a biopsy in a few weeks. She also suspects that my stomach lining has eroded, so that in itself may be the problem. I went gluten-free for about a month do to suspected allergies (I know it's not the same, but a nutrionist suggested I give it a try). I did feel better in that time, but starting eating some gluten again after some craziness with my food allergies. Now I'm really trying to eat gluten to make sure my biopsy results are accurate. I'm not feeling great, so I won't be surprised if the biopsy shows Celiac.

Anyway, has anyone ever had a negative result in their bloodwork, but then been positive for Celiac after a biopsy?

Thanks!

Cici

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My blood test showed negative for Celiac in late May, but since I have many of the symptoms, by doc is going to do a biopsy in a few weeks. She also suspects that my stomach lining has eroded, so that in itself may be the problem. I went gluten-free for about a month do to suspected allergies (I know it's not the same, but a nutrionist suggested I give it a try). I did feel better in that time, but starting eating some gluten again after some craziness with my food allergies. Now I'm really trying to eat gluten to make sure my biopsy results are accurate. I'm not feeling great, so I won't be surprised if the biopsy shows Celiac.

Anyway, has anyone ever had a negative result in their bloodwork, but then been positive for Celiac after a biopsy?

Thanks!

Cici

Yes, my daughter's bloodwork was negative, but the biopsy came back positive. It took years to find out what her problem was. Good luck!

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Yes, I had my biopsy first (they were looking for ulcers, not celiac, but did some SI biopsies any way "just because they were there..."). I had the blood tests a week later, but they were all negative. I didn't have flattened or blunted villi, just microscopic damage, immune system response etc. at the cellular level.

I think I was lucky to be diagnosed.

My blood test showed negative for Celiac in late May, but since I have many of the symptoms, by doc is going to do a biopsy in a few weeks. She also suspects that my stomach lining has eroded, so that in itself may be the problem. I went gluten-free for about a month do to suspected allergies (I know it's not the same, but a nutrionist suggested I give it a try). I did feel better in that time, but starting eating some gluten again after some craziness with my food allergies. Now I'm really trying to eat gluten to make sure my biopsy results are accurate. I'm not feeling great, so I won't be surprised if the biopsy shows Celiac.

Anyway, has anyone ever had a negative result in their bloodwork, but then been positive for Celiac after a biopsy?

Thanks!

Cici


Diagnosed by biopsy 2/12/07. Negative blood tests. Gluten-free (except for accidents) since 2/15/07. DQ2.5 (HLA DQA1*05:DQB1*0201)

Son, age 18, previously delayed growth 3rd percentile weight, 25th percentile height (5'3" at age 15). Negative blood work. Endoscopy declined. Enterolab positive 3/12/08. Gene results: HLA-DQB1 Molecular analysis, Allele 1 0201 HLA-DQB1 Molecular analysis, Allele 2 0503 Serologic equivalent: HLA-DQ 2,1(Subtype 2,5) Went gluten-free, casein-free 3/15/08. Now 6'2" (Over six feet!) and doing great.

"Great difficulties may be surmounted by patience and perseverance." Abigail Adams (1744-1818) 2nd First Lady of the United States

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Thanks. I'm nervous my biopsy is going to be negative, even thought I think gluten is part of my problem. I'm trying to eat a lot of gluten until then. I don't feel wonderful, of course, but I'd rather have an accurate diagnosis. I think I will go gluten-free even if I'm not positive to Celiac. I think it would help me have less symptoms.

Cici

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