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Been Reading Interpertation Information


Linda56

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Linda56 Apprentice

I have been rereading the interpretations information page about test. Is it that I have DQ2 a main gene but it would be more serious if I had an 2 beside the DQ2 than having the 3. A 2 would make it a double gene. Then the 3 is a non-gluten sensitve gene. What is the subtype 2,7 in paratheses for if any thing? Because I don't have double gene then the risk can be less severe possibly than those of you that have DQ2 2 for example. Sorry to go on about this hopefully I finally got it figured out. as far as reading the test. Thanks

Gluten Sensitivity Gene Test

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0301

Serologic equivalent: HLA-DQ 2,3 (Subtype 2,7)

Interpretation Of HLA-DQ Testing: HLA gene analysis reveals that you have one of the main genes that predisposes to gluten sensitivity and celiac sprue, HLA-DQ2 or HLA-DQ8. Each of your offspring has a 50% chance of receiving this gene from you, and at least one of your parents passed it to you. You also have a non-celiac gene predisposing to gluten sensitivity (DQ1 or DQ3 not subtype 8). Having one celiac gene and one gluten sensitive gene, means that each of your parents, and all of your children (if you have them) will possess at least one copy of a gluten sensitive gene. Having two copies also means there is an even stronger predisposition to gluten sensitivity than having one gene and the resultant immunologic gluten sensitivity or celiac disease may be more severe.

Lin


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