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What Tests Should I Have Done For Celiac?


SLB5757

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SLB5757 Enthusiast

Hello again!

First I want to say thank you for all the responses, and support on my previous post. I had one more question that I would liek to see if anyone can help with. I live in a small town and I do not think the physicians here are very "up to speed" on Celiac disease or the testing required for it.

I had a celiac test that came back negative a year ago. My doc had sent out bloodwork to an outside facility. I have asked that it be faxed to me so I can be more specific as to exactly what test it was. I also had an endoscopy two years ago - and I do not believe they did a biopsy for celiac at that time since they believed I had GERD. I have called the gastro that I went to to check and see if one was done at that time.

So my question is:

What specific tests should be done to rule out celiac? I have seen "Enterolab" on this board, and "IG something", and the biopsy via scope as being the "gold standard" for detection.

Thanks!!!


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Lisa Mentor
So my question is:

What specific tests should be done to rule out celiac? I have seen "Enterolab" on this board, and "IG something", and the biopsy via scope as being the "gold standard" for detection.

Thanks!!!

This is the panel that you should begin with:

Anti-gliadin antibodies (AGA) both IgA and IgG

Anti-endomysial antibodies (EMA) - IgA

Anti-tissue transglutaminase antibodies (tTG) - IgA

Total IgA level.

(you should remain on a full gluten diet for many weeks to aid in it's accuracy)

Unfortunately, testing is not as accuracy as we would like at this time. The Serologic Blood panel can rule Celiac in, but it cannot rule it out, as with the endoscopy/biopsy.

SLB5757 Enthusiast
This is the panel that you should begin with:

Anti-gliadin antibodies (AGA) both IgA and IgG

Anti-endomysial antibodies (EMA) - IgA

Anti-tissue transglutaminase antibodies (tTG) - IgA

Total IgA level.

(you should remain on a full gluten diet for many weeks to aid in it's accuracy)

Unfortunately, testing is not as accuracy as we would like at this time. The Serologic Blood panel can rule Celiac in, but it cannot rule it out, as with the endoscopy/biopsy.

I just received the test back from my doctors that was done April of last year. They sent blood to the Mayo Clinic lab. The test that was ordered says Endomysial Abs, S (IgA). It says "negative" and that is the only words listed on the report. No levels as in numbers...just the words "negative".

The report states:

Test requested: Endomysial Abs, S (IgA)

Hi/Lo: Negative

Ref Range: Negative

Perform Site: MCR

My doc who is a CNP - just mailed it to me and said " your test for Celiac disease was negative". I may look into the other tests you have mentioned above. Thank-you.

Lisa Mentor
I just received the test back from my doctors that was done April of last year. They sent blood to the Mayo Clinic lab. The test that was ordered says Endomysial Abs, S (IgA). It says "negative" and that is the only words listed on the report. No levels as in numbers...just the words "negative".

The report states:

Test requested: Endomysial Abs, S (IgA)

Hi/Lo: Negative

Ref Range: Negative

Perform Site: MCR

My doc who is a CNP - just mailed it to me and said " your test for Celiac disease was negative". I may look into the other tests you have mentioned above. Thank-you.

Here is additional information you might find important:

Open Original Shared Link

AWonderTree Rookie

I don't mean to hijack this thread, but I basically have the same question as the topic's starter.

I'm feeling stupid because I'm having trouble understanding which tests weren't done on my report:

Reticulin Abs, S: Negative

Endomysial Abs, S: Negative

Gliadin(Deamidated) Ab, IgA, S: 2.9; <20.0 (Negative)

Gliadin(Deamidated) Ab, IgG, S: <1.0; <20.0 (Negative)

My questions:

  • What do these words and abbreviations mean: Abs, S, deamidated, Ab?
  • Are the first two any of the following (that I've read should be done)?
    Anti-gliadin antibodies (AGA) both IgA and IgG
    Anti-endomysial antibodies (EMA) - IgA
    Anti-tissue transglutaminase antibodies (tTG) - IgA
    Total IgA level.
  • Am I right to think that the last two on my report are "Anti-gliadin antibodies (AGA) both IgA and IgG"?
  • And the rest seem to be completely skipped. Hmmm.

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