Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Test Result Inconclusive


sdshepherd

Recommended Posts

sdshepherd Newbie

Hi, I am new here, i have had trouble my entire life with bloating, gas, stools, phsorias, sinus problems, lactose intolorance, and others like i always felt like I was hungry all the time, litterally i would set down and eat two large hamburgers, with all the fixins, and then an hour lateer I was litterally starving, as a child I was super skinny, and was allergic to everything coming and going, was always sick, then at 14 my appendix ruptured and everything stopped , from then on I eat all the time and gainned weight... well finally I just got tired of the digestive problems, and started researching, and started reading about celiac, well it was like a bright light, so I went and got tested, but the results came back inconclusive, and I also have very low vitamin D, so I am on 50,000ui a week for the next 8 weeks. What does the inconclusive mean???


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



leadmeastray88 Contributor
What does the inconclusive mean???

Not sure. To know, we'd have to see exactly what they tested. You can ask your doctor for a copy of the lab results and post them here so we can help.

It could mean that you were 'borderline positive', (which is still positive) but your doc didn't think that it means you have Celiac...

Again, we'd need to see the lab results :)

sdshepherd Newbie

Ok here are the lab results

tissue Transglutaminase Antibody on a scale of 5-8 I scored a 3 (this one showed a negative)

Immunoglobulin A on a scale of 81-463 I scored a 510 (this one showed a positive)

thus with a negative and a positive, they told me that my results where inconclusive and they referred me to a GI doc.

Mother of Jibril Enthusiast

Ah... the only reason your test is "inconclusive" is because it's incomplete.

Here's what a full panel should include:

Anti-gliaden IgA

Anti-gliaden IgG

Tissue transglutaminase IgA

Tissue transglutaminase IgG

Endomysial antibodies

Total IgA

The two tests you had were Ttg IgA and total IgA. Your number for IgA (510) just means you're not deficient... nothing to worry about. People who ARE deficient can easily get a false negative. The fact that you were negative for ttg IgA doesn't mean much. It's just one test. You could definitely still have celiac disease. Keep eating gluten and go to that next appointment! Hopefully the GI will do a full panel and/or a biopsy (endoscopy).

Incidentally... I was also that skinny kid who could never get enough to eat. Until my thyroid was destroyed. That's when the weight gain and digestive problems started <_<

sdshepherd Newbie

How do they do a biopsy??

sdshepherd Newbie
Ah... the only reason your test is "inconclusive" is because it's incomplete.

Here's what a full panel should include:

Anti-gliaden IgA

Anti-gliaden IgG

Tissue transglutaminase IgA

Tissue transglutaminase IgG

Endomysial antibodies

Total IgA

The two tests you had were Ttg IgA and total IgA. Your number for IgA (510) just means you're not deficient... nothing to worry about. People who ARE deficient can easily get a false negative. The fact that you were negative for ttg IgA doesn't mean much. It's just one test. You could definitely still have celiac disease. Keep eating gluten and go to that next appointment! Hopefully the GI will do a full panel and/or a biopsy (endoscopy).

Incidentally... I was also that skinny kid who could never get enough to eat. Until my thyroid was destroyed. That's when the weight gain and digestive problems started <_<

Yeah its funny, both my maternal grandparents died of colon cancer, I have a great aunt with crones disease, and my great grandmother had thyroid cancer... not to mention all the allergies in my family...

leadmeastray88 Contributor
How do they do a biopsy??

To biopsy, they do a procedure called an endoscopy - basically they insert a small tube down your throat with a little camera on it, they descend into your small intestine and take small biopsies through the tube.

Many people here have had this done and say it's a breeze - I know there's anesthetic/sedation options as well.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - trents replied to catnapt's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      5

      how much gluten do I need to eat before blood tests?

    2. - MauraBue posted a topic in Gluten-Free Foods, Products, Shopping & Medications
      0

      Have Tru Joy Sweets Choco Chews been discontinued??

    3. - catnapt replied to catnapt's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      5

      how much gluten do I need to eat before blood tests?

    4. - suek54 replied to suek54's topic in Dermatitis Herpetiformis
      7

      Awaiting dermatitis herpetiformis confirmation following biopsy

    5. - knitty kitty replied to suek54's topic in Dermatitis Herpetiformis
      7

      Awaiting dermatitis herpetiformis confirmation following biopsy

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,260
    • Most Online (within 30 mins)
      7,748

    MauraBue
    Newest Member
    MauraBue
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • trents
      The rate of damage to the villous lining of the SB and the corresponding loss of nutrient absorbing efficiency varies tremendously from celiac to celiac. Yes, probably is dose dependent if, by dose dependent you mean the amount of exposure to gluten. But damage rates and level of sensitivity also seem to depend on the genetic profile. Those with both genes HLA-DQ2 and HLA-DQ8 seem to be more sensitive to minor amounts of gluten exposure than those with just one of those genes and those with only DQ2 seem to be more sensitive than those with only DQ8. But there are probably many factors that influence the damage rate to the villi as well as intensity of reaction to exposure. There is still a lot we don't know. One of the gray areas is in regard to those who are "silent" celiacs, i.e. those who seem to be asymptomatic or whose symptoms are so minor that they don't garner attention. When they get a small exposure (such as happens in cross contamination) and have no symptoms does that equate to no inflammation? We don't necessarily know. The "sensitive" celiac knows without a doubt, however, when they get exposure from cross contamination and the helps them know better what food products to avoid.
    • MauraBue
      Help!  My 5 year old daughter just stopped eating dairy and gluten due to her EoE and Celiac.  Her favorite candy in the world is tootsie rolls.  I did some research, and it sounds like these are the only options for finding something similar, but I can't find them anywhere to actually purchase.  Have they been discontinued??  Does anyone have another recommendation for a gluten-free/DF tootsie roll option?
    • catnapt
      I wonder how long it usually takes and if it is dose dependent as well... or if some ppl have a more pronounced reaction to gluten than others   thanks again for all the great info    
    • suek54
      Wow KK, thank you so much for all your attached info. I had a very quick scan but will read more in depth later.  The one concerning corticosteroid use is very interesting. That would relate to secondary adrenal insufficiency I think , ie AI caused by steroids such as taken long term for eg asthma. I have primary autoimmune AI, my adrenals are atrophied, no chance if recovery there. But I am in touch with some secondaries, so something to bear in mind. .  Niacin B3 Very interesting too. Must have a good read about that.  Im sure lots of questions will arise as I progress with dermatitis herpetiformis. In the mean time, thanks for your help.
    • knitty kitty
      Welcome to the forum, @suek54, I have Dermatitis Herpetiformis, too.  I found taking Niacin B3 very helpful in clearing my skin from blisters as well as improving the itchies-without-rash (peripheral neuropathy).  Niacin has been used since the 1950's to improve dermatitis herpetiformis.   I try to balance my iodine intake (which will cause flairs) with Selenium which improves thyroid function.   Interesting Reading: Dermatitis herpetiformis effectively treated with heparin, tetracycline and nicotinamide https://pubmed.ncbi.nlm.nih.gov/10844495/   Experience with selenium used to recover adrenocortical function in patients taking glucocorticosteroids long https://pubmed.ncbi.nlm.nih.gov/24437222/   Two Cases of Dermatitis Herpetiformis Successfully Treated with Tetracycline and Niacinamide https://pubmed.ncbi.nlm.nih.gov/30390734/   Steroid-Resistant Rash With Neuropsychiatric Deterioration and Weight Loss: A Modern-Day Case of Pellagra https://pmc.ncbi.nlm.nih.gov/articles/PMC12532421/#:~:text=Figure 2.,(right panel) upper limbs.&text=The distribution of the rash,patient's substantial response to treatment.   Nicotinic acid therapy of dermatitis herpetiformis (1950) https://pubmed.ncbi.nlm.nih.gov/15412276/
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.