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Diagnos-Techs Saliva Test: Any Good?


Chicago123

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Chicago123 Newbie

I had a test done with Diagnos techs on my GP's reco for my IBS. It came out positive for Gluten:

Gliadin Ab, SIgA 38, Ranges( Boderline 13-15, Positive >15).

Based on this I had my biopsies and blood done, both of which came back clearly negative for celiac (no villi damage).

I am really clueless now. Any experiences with Daignostechs saliva test?

Thanks!


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mushroom Proficient

I had stool and saliva testing done with Diagnos-Techs six months after I quit gluten. I am really not sure which results derived from salive and which from stool (although obviously the fecal fat came from stool :P) My gliadin was still high, it picked up my soy and corn intolerances, but told me I was intolerant to egg and casein which was not the case. So I really don't know how to evaluate their testing.

Regardless, it is still possible to have gluten intolerance with negative bloodwork and biopsy, in fact about a 20% error rate according to whom you believe, not accounting for those who are not yet damaged sufficiently to test positive on these tests (the ranges are purposely set high to eliminate false positives, of which I have never heard).

Your next step is to go strictly on the gluten free diet for at least three months and see what difference it makes to your life. You may be joyfully surprised.

Skylark Collaborator

What does your doctor say about the false positive rate of this test?

There is no harm in trying the diet to see whether it helps you out.

Matisse Newbie

I had a test done with Diagnos techs on my GP's reco for my IBS. It came out positive for Gluten:

Gliadin Ab, SIgA 38, Ranges( Boderline 13-15, Positive >15).

Based on this I had my biopsies and blood done, both of which came back clearly negative for celiac (no villi damage).

I am really clueless now. Any experiences with Daignostechs saliva test?

Thanks!

I had a positive saliva Gliadin test (25) at Diagnos-Techs also. This was after being gluten free for a little over 4 months. Also tested positive for the deamidated gliadin IGG blood test (33.9) 4 months earlier before going gluten free. I am negative for the DQ2 and 8 genes. More recently I was retested with the deamidated gliadin test and am now at 13 (IGG antibodies). The 13 is still positive but has dropped from 33.9 after 9 months of a gluten free diet. Also had a positive saliva test for soy at Diagnos-Techs.

What celiac blood tests did you have done?

  • 2 weeks later...
Chicago123 Newbie

I had a positive saliva Gliadin test (25) at Diagnos-Techs also. This was after being gluten free for a little over 4 months. Also tested positive for the deamidated gliadin IGG blood test (33.9) 4 months earlier before going gluten free. I am negative for the DQ2 and 8 genes. More recently I was retested with the deamidated gliadin test and am now at 13 (IGG antibodies). The 13 is still positive but has dropped from 33.9 after 9 months of a gluten free diet. Also had a positive saliva test for soy at Diagnos-Techs.

What celiac blood tests did you have done?

Here are the tests I got done:

TTG IgG 0.5 ( <6 is negative)

ENDOMYSIAL IgA <1:10 (<1:10 is negative)

TTG IgA <0.4 (< 4 is negative)

So I wasnt even borderline close. Irrespective, I tries gluten free for a while. I think I felt slightly better, but that could be because I went on a very light diet all together. So my guess is Diagnos Techs is not really reliable.

ravenwoodglass Mentor

Here are the tests I got done:

TTG IgG 0.5 ( <6 is negative)

ENDOMYSIAL IgA <1:10 (<1:10 is negative)

TTG IgA <0.4 (< 4 is negative)

So I wasnt even borderline close. Irrespective, I tries gluten free for a while. I think I felt slightly better, but that could be because I went on a very light diet all together. So my guess is Diagnos Techs is not really reliable.

Keep up with the diet strictly for a bit. The blood tests are not as reliable as we would like. Your body will tell you the answer if you give the diet a chance.

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