Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Test Results

MissKris2

Recommended Posts

MissKris2 Newbie
MissKris2
Posted

Hi everyone! I had some labs done recently and. First, I should say that I was almost entirely gluten-free for 2 months recently. I started eating gluten again so that I could possibly get a diagnosis. I had been eating gluten for about 3 weeks prior to the labs being done.

Deadimated Gliadin Abs, IgA 4 (0-19)

Deadimated Gliadin Abs, IgG 2 (0-19)

t-Transglutaminase IgA <2 (0-3)

t-Transglutaminase IgG 21 (>9 is strong positive)

So, the only thing I tested positive for was the tTG IgG.

My doctors don't seem to know much about gluten intolerance. I have a biopsy in about a month. Just wondering if anyone had any thoughts on the test results. Thanks!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


JoshB Apprentice
JoshB
Posted

Transglutaminase IgG is concidered a little less reliable than ttG IgA, but everything I read says it is still very reliable, and you seem to have a strong positive. If it were me I would forgo the biopsy unless I needed it for insurance reasons or your own peace of mind. You already have a positive reading for a test which is more accurate than the biopsy. The biopsy might help you figure out how much damage you've already got, however.

It's a little strange that your ttg-IgA would be so relatively low. It's possible to have some general immune system deficiencies that can influence that. This is usually tested for in a celiac panel, but didn't seem to be in your case.

Open Original Shared Link

MissKris2 Newbie
MissKris2
Posted
  • Author

Thanks for replying! The panel did also include Endomysial Antibody IgA (negative) and Immunoglobin A, Qn, Serum which was 126 (70-400=normal). Sorry, I guess I should have included that info. It's frustrating when it seems like the doctors don't know any more about it than I do (and sometimes less!).

JoshB Apprentice
JoshB
Posted

They generally don't know as much, and as easy as it is to get angry about that, it's not really their fault. It's a very hard disease to catch, and a fairly small number of people have it. How much would you learn if you were a doctor and had two patients with a particular disease that they saw another specialist about anyway. If it even looks like you might have it you've probably gone and read 10X more on the subject than your doctor has ever come across. And remember what your GP doctor has seen is half remembered and thirty years out of date from med-school.

MissKris2 Newbie
MissKris2
Posted
  • Author

I know. I'm not angry, just frustrated. Especially when the doctors think I'm a hypochondriac and that all of my symptoms are from "stress." Anyway, thanks again for replying!

MissKris2 Newbie
MissKris2
Posted
  • Author

I guess I'm wondering if the positive tTG IgG is irrelevant if I'm not IgA deficient.

pain*in*my*gut Apprentice
pain*in*my*gut
Posted

I guess I'm wondering if the positive tTG IgG is irrelevant if I'm not IgA deficient.

No, it's not irrelevant. It is entirely possible that you do have something going on, and I would go ahead with the biopsy, especially if you are symptomatic.

Immunology is a very tricky science, and it is wrought with inconsistencies and the unexplained. I used to work in the field (I'm a med tech), and sometimes it's impossible to get a perfect picture of what a disease "should" look like on paper.

It makes me angry (yes, angry) when doctors disregard patients because they don't fit the "typical" picture. I understand that they are taught in med school that "if you hear hoof beats, look for horses, not zebras". But if the patient has proven themselves to not be a horse, it's time to see if they might be a zebra!! :angry:

I could go on, but I won't. I ate to much gluten today (stupid gluten challenge) that I feel like I am going to barf.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


JoshB Apprentice
JoshB
Posted

I know. I'm not angry, just frustrated. Especially when the doctors think I'm a hypochondriac and that all of my symptoms are from "stress." Anyway, thanks again for replying!

Heh. My stomach troubles were "stress" from when I was six.

MissKris2 Newbie
MissKris2
Posted
  • Author

Thanks for your reply, pain*in*my*gut! I know what you mean about doctors discounting you because you're not the "typical" celiac. Luckily the nurse practitioner at my GI office is more open-minded because she has family who had atypical symptoms of celiac disease, but even she isn't extremely knowledgeable on the subject. I guess we'll see what happens with the biopsy :rolleyes:.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,540
    • Most Online (within 30 mins)
      7,748
    Barrie S
    Newest Member
    Barrie S
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • knitty kitty
      Unusual bright yellow but odourless discharge

      By knitty kitty · Posted

      Yes, I, too, have osteoporosis from years of malabsorption, too.  Thiamine and magnesium are what keep the calcium in place in the bones.  If one is low in magnesium, boron, selenium, zinc, copper, and other trace minerals, ones bone heath can suffer.  We need more than just calcium and Vitamin D for strong bones.  Riboflavin B 2, Folate B 9 and Pyridoxine B 6 also contribute to bone formation and strength.   Have you had your thyroid checked?  The thyroid is important to bone health as well.  The thyroid uses lots of thiamine, so a poorly functioning thyroid will affect bone heath.  
    • Celiac50
      Unusual bright yellow but odourless discharge

      By Celiac50 · Posted

      That sounds so very likely in my case! I will absolutely ask my doctor on my next bone check coming up in March... Thanks a lot! 
    • trents
      Unusual bright yellow but odourless discharge

      By trents · Posted

      Calcium levels as measured in the blood can be quite deceiving as the body will rob calcium from the bones to meet demands for it by other bodily functions. Also, supplementing with calcium can be counterproductive as it tends to raise gut pH and decrease absorption. More often than not, the problem is poor absorption to begin with rather than deficiency of intake amounts in the diet. Calcium needs an acidic environment to be absorbed. This is why so many people on PPIs develop osteoporosis. The PPIs raise gut pH. And some people have high gut PH for other reasons. Low pH equates to a more acidic environment whereas high pH equates to a more basic (less acidic) environment.
    • Celiac50
      Unusual bright yellow but odourless discharge

      By Celiac50 · Posted

      Kind thanks for all this valuable information! Since my Folate was/is low and also my Calcium, there IS a chance I am low in B vitamins... My doctor only measured the first two, oh and Zinc as I has twisted her arm and guess what, that was mega low too. So who knows, until I get myself tested properly, what else I am deficient in... I did a hair mineral test recently and it said to avoid All sources of Calcium. But this is confusing for me as my Ca is so low and I have osteoporosis because of this. It is my Adjusted Ca that is on the higher side and shouldn't be. So am not sure why the mineral test showed high Ca (well, it was medium in the test but relative to my lowish Magnesium, also via hair sample, it was high I was told). But anyway, thanks again for the VitB download, I will look into this most certainly!
    • ElisaAllergiesgluten
      Allergy medication: cetirizine by the HealthA2Z is it gluten free?

      By ElisaAllergiesgluten · Posted

      Hello good afternoon, I was wondering if anyone has ever brought their anti-allergy pills? I have been wanting to use their Cetirizine HCI 10mg. They are called HealthA2Z and distributed by Allegiant Health.I’m also Asthmatic and these allergies are terrible for me but I also want to be sure they don’t have any sort of gluten compound.    I have tried calling them but to no avail. Has anyone ever used them? If so, did you had any problems or no problems at all?    thank you
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.