Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Any Lab That Offers Full Hla-Dq Gene Testing?

alicewa

Recommended Posts

alicewa Contributor
alicewa
Posted

Hi,

I wanted to be genetically tested for which HLA-DQ alleles that I possess. Most labs only tell you whether you have the celiac alleles.

Enterolab tells us what HLA-DQB1 are present but not the A1 subunits.

Is there any lab that does a full analysis of both the HLA-DQA1 and B1 subunits?

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


beachbirdie Contributor
beachbirdie
Posted

Hi,

I wanted to be genetically tested for which HLA-DQ alleles that I possess. Most labs only tell you whether you have the celiac alleles.

Enterolab tells us what HLA-DQB1 are present but not the A1 subunits.

Is there any lab that does a full analysis of both the HLA-DQA1 and B1 subunits?

You can get tested through Open Original Shared Link. You get the Prometheus testing, they do the A1 and B1 subunits. The one you can order yourself is a saliva test, supposed to be accurate, and costs $329.

alicewa Contributor
alicewa
Posted
  • Author

I believe the labs you mentioned only check for celiac genes. I wondered if there were any that actually assessed which of the HLA-DQ genes you have rather than whether you have HLA-DQ2/DQ8. :unsure:

Enterolab is one but the only do the beta subunit. :huh:

I need to find one that also does the alpha subunit.

Bubba's Mom Enthusiast
Bubba's Mom
Posted

My test was done at the Mayo Clinic. It lists both alpha and beta. My Dr. ordered the test and had it sent there. They do testing for people all over the country.

beachbirdie Contributor
beachbirdie
Posted

I believe the labs you mentioned only check for celiac genes. I wondered if there were any that actually assessed which of the HLA-DQ genes you have rather than whether you have HLA-DQ2/DQ8. :unsure:

Enterolab is one but the only do the beta subunit. :huh:

I need to find one that also does the alpha subunit.

Are you looking for a way to get testing without a Dr. order?

Open Original Shared Link does it I think, according to an article on the front page of this site. Prometheus and Kimball are the ones you see through the University of Chicago Celiac Center. They do a Open Original Shared Link every fall.

https://www.celiac.com/articles/21567/1/Ten-Facts-About-Celiac-Disease-Genetic-Testing/Page1.html

alicewa Contributor
alicewa
Posted
  • Author

I was hoping to find a test where they list the two alleles that you DO possess (even if they aren't celiac alleles)

(e.g. HLA-DQs2,4,5,6,7,8,9)

Dr Peter Osborne said there are only two labs in the whole country that evaluate WHAT HLA-DQ genes you have rather than whether you possess the celiac gene. Let's just assume I'm willing to pay anything for now.

Would you happen to know of one that not only tests for the presence of HLA-DQ2/DQ8 but rather all of them?

Thanks in advance.

beachbirdie Contributor
beachbirdie
Posted

I was hoping to find a test where they list the two alleles that you DO possess (even if they aren't celiac alleles)

(e.g. HLA-DQs2,4,5,6,7,8,9)

Dr Peter Osborne said there are only two labs in the whole country that evaluate WHAT HLA-DQ genes you have rather than whether you possess the celiac gene. Let's just assume I'm willing to pay anything for now.

Would you happen to know of one that not only tests for the presence of HLA-DQ2/DQ8 but rather all of them?

Thanks in advance.

Ahh. I did not understand that you were looking to see which of the 9 types you might have.

Apparently you can possibly get full typing through Open Original Shared Link, but you'd probably have to have a doctor order them. You could contact Quest and ask if there is a way to self-order, I imagine it will be expensive.

Enterolab can supposedly do it (one article said they contract with Bonfils), but you will also have to ask specifically how many alleles they'll test for and what the cost is.

Open Original Shared Link(actually the parent of Kimball Genetics) does genetic testing. You'd have to call them to find out the details. There were more HLA tests on their site than on Kimball's.

Some of the patient-directed lab services contract with labcorp, you might contact one of them too. Open Original Shared Link is one. They don't post comprehensive offerings on their sites, you won't find what you're looking for unless you call or email them.

I found a forum where people were discussing this, some posters said that these labs only do the beta unit, not the alpha. You'll have to question carefully. You might not be able to find what it is you are looking for.

Just curious, why are you wanting all the alleles? I've been curious, as I have autoimmune thyroid, about whether I have the DQ5 or DQ7 that often associate.

Interesting articles here:

Open Original Shared Link

https://www.celiac.com/celiac-disease/understanding-the-genetics-of-gluten-sensitivity-by-dr-scot-lewey-r1032/

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


  • 1 year later...
ClinicalNutritionist Newbie
ClinicalNutritionist
Posted

I used TrueHealthLabs.com Open Original Shared Link  and the test for HLA-DQ 2 and 8 along with the alpha and beta units.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,542
    • Most Online (within 30 mins)
      7,748
    Carol Zimmer
    Newest Member
    Carol Zimmer
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Jsingh
      Protein or fat?

      By Jsingh · Posted

      Hi,  I care for my seven year old daughter with Celiac. After watching her for months, I have figured out that she has problem with two kinds of fats- animal fat and cooking oils. It basically makes her intestine sore enough that she feels spasms when she is upset. It only happens on days when she has eaten more fat than her usual every day diet. (Her usual diet has chia seeds, flaxseeds, and avocado/ pumpkin seeds for fat and an occasional chicken breast.) I stopped using cooking oils last year, and when I reintroduced eggs and dairy, both of which I had held off for a few months thinking it was an issue of the protein like some Celiac patients habe mentioned to be the case, she has reacted in the same fashion as she does with excess fats. So now I wonder if her reaction to dairy and eggs is not really because of protein but fat.   I don't really have a question, just wondering if anyone finds this familiar and if it gets better with time.  Thank you. 
    • Chanda Richard
      High Cost of Gluten-Free Foods

      By Chanda Richard · Posted

      Hello, My name is Chanda and you are not the only one that gose through the same things. I have found that what's easiest for me is finding a few meals each week that last. I have such severe reactions to gluten that it shuts my entire body down. I struggle everyday with i can't eat enough it feels like, when I eat more I lose more weight. Make sure that you look at medication, vitamins and shampoo and conditioner also. They have different things that are less expensive at Walmart. 
    • petitojou
      Frequent nausea after gluten-free diet

      By petitojou · Posted

      Thank you so much! I saw some tips around the forum to make a food diary and now that I know that the community also struggles with corn, egg and soy, the puzzle pieces came together! Just yesterday I tried eating eggs and yes, he’s guilty and charged. Those there are my 3 combo nausea troublemakers. I’m going to adjust my diet ☺️ Also thank you for the information about MCAS! I’m from South America and little it’s talked about it in here. It’s honestly such a game changer now for treatment and recovery. I know I’m free from SIBO and Candida since I’ve been tested for it, but I’m still going to make a endoscopy to test for H. Pylori and Eosinophilic esophagitis (EoE). Thank you again!! Have a blessed weekend 🤍
    • knitty kitty
      Unusual bright yellow but odourless discharge

      By knitty kitty · Posted

      Yes, I, too, have osteoporosis from years of malabsorption, too.  Thiamine and magnesium are what keep the calcium in place in the bones.  If one is low in magnesium, boron, selenium, zinc, copper, and other trace minerals, ones bone heath can suffer.  We need more than just calcium and Vitamin D for strong bones.  Riboflavin B 2, Folate B 9 and Pyridoxine B 6 also contribute to bone formation and strength.   Have you had your thyroid checked?  The thyroid is important to bone health as well.  The thyroid uses lots of thiamine, so a poorly functioning thyroid will affect bone heath.  
    • Celiac50
      Unusual bright yellow but odourless discharge

      By Celiac50 · Posted

      That sounds so very likely in my case! I will absolutely ask my doctor on my next bone check coming up in March... Thanks a lot! 
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.