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  • Jefferson Adams
    Jefferson Adams

    Ancient Wheat Strains Trigger Adverse Reactions in People with Celiac Disease

    Reviewed and edited by a celiac disease expert.
    Ancient Wheat Strains Trigger Adverse Reactions in People with Celiac Disease - Photo: Wikimedia Commons SA3.0
    Caption: Photo: Wikimedia Commons SA3.0

    Celiac.com 11/11/2014 - There have been claims that certain strains of wheat, especially ancient strains, such as einkorn, do not trigger adverse reactions in people with celiac disease, or that they trigger less severe reactions.

    Until now, researchers haven't been able to say for certain that celiac disease patients react adversely to all varieties of wheat, or whether there may be differences in reactions to certain strains.

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    A research team recently evaluated the safety of ancient strains of wheat in celiac disease. The researchers included Tanja Šuligojemailemail, Armando Gregorinidemail, Mariastella Colombaeemail, H. Julia Elliscemail, and Paul J. Ciclitirac

    To get a better idea of the nature of celiac factions to wheat, the team studied seven Triticum accessions showing different origin (ancient/modern) and ploidy (di-, tetra- hexaploid).

    In all, they tested ancient Triticum monococcum precoce (AA genome) and Triticum speltoides (BB genome), accessions of Triticum turgidum durum (AABB genome) including two ancient (Graziella Ra and Kamut) and two modern (Senatore Cappelli and Svevo) durum strains of wheat and Triticum aestivum compactum (AABBDD genome).

    They evaluated small intestinal gluten-specific T-cell lines generated from 13 celiac patients with wheat accessions by proliferation assays. They found that all strains of wheat they tested triggered a range of adverse responses, independent of ploidy or ancient/modern origin.

    Based on these results, they suggest that all strains of wheat, even ancient strains previously suggested to be low or devoid of celiac toxicity, should be tested for immunogenicity using gluten-specific T-cell lines from multiple celiac patients rather than gluten-specific clones to assess their potential toxicity.

    They also emphasize the need for celiac patients to follow a strict gluten-free diet, including avoidance of ancient strains of wheat.

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    Guest Diana Thompson

    Posted

    My worst point in my illness, I consumed little to no wheat, but ate spelt and kamut. I was in TROUBLE! Please take this to heart and do not try older varieties of wheat thinking it will be same.

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    Guest Jefferson

    Posted

    My worst point in my illness, I consumed little to no wheat, but ate spelt and kamut. I was in TROUBLE! Please take this to heart and do not try older varieties of wheat thinking it will be same.

    An excellent point, Diana. Thanks for your comment.

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    Guest Zsolt Kanyo

    Posted

    In Hungary a researcher and colleagues found the same relations.

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    Guest Joe

    I basically go into a coma for a few hours after eating wheat.  With Einkorn I do much better.  Is einkorn completely safe?  Or does it just do a little bit of harm?  Hard to say.  With the whole grain you run into wheat germ agglutinin problems also.

    The question may not be if the immune system reacts, but maybe if it's digestible, i.e. chopped up before you can absorb it.  

    I made some very good einkorn pizza and if it's something we can eat, that is surely worth knowing.

    Of note, Corn has "gluten" in it, but it's a different thing than wheat gluten.  

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  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

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