Celiac.com 07/26/2021 - Cases of chronic inflammatory autoimmune conditions, such as celiac disease are rising at a rate that concerns many researchers. 
To better understand the etiology and pathogenesis of celiac disease, especially the role of environmental stimuli, and gut microbiota in connection with the immune system, a team of researchers recently conducted a study, in which they did both cross-sectional and longitudinal analysis of gut microbiota, functional pathways, and metabolites, starting from 18 months before celiac disease onset in 10 infants who developed celiac, compared with 10 infants who did not. 
The research team included Maureen M. Leonard, Francesco Valitutti, Hiren Karathia, Meritxell Pujolassos, Victoria Kenyon, Brian Fanelli, Jacopo Troisi, Poorani Su...

Celiac.com 03/06/2023 - We get a lot of questions about celiac disease and gluten-free-related issues. One question we've seen lately is: Is there a connection between the human gut microbiome and celiac disease? The short answer is yes. The longer answer is that research has show a number of connections between the two conditions, but we still have far more questions than answers. Here's a rundown of what we do know.
Celiac disease is an autoimmune disorder that affects the small intestine. When individuals with celiac disease consume gluten, a protein found in wheat, barley, and rye, it triggers an immune response that damages the lining of the small intestine and interferes with the absorption of nutrients.
One of the key components of the gut environment is the microbiome,...

Celiac.com 12/25/2025 - Celiac disease is an intestinal condition triggered when genetically susceptible people eat foods that contain gluten. Gluten is a group of proteins found in wheat, barley, and rye. Although genes and gluten exposure are both needed for the disease to develop, not everyone who has the risk genes becomes sick. This has led scientists to explore other contributors, especially those involving the digestive system and the microorganisms living inside the intestine. Recent research suggests that the gut environment plays an important part in determining whether a person with the necessary genes will eventually develop the disease.
The study summarized here examined Chinese adults living in Xinjiang who were diagnosed with celiac disease and then compared them with...

Celiac.com 01/15/2026 - Celiac disease has long been viewed as a condition that appears suddenly—first with vague digestive issues, then with clear serological markers, and finally with intestinal damage diagnosed through biopsy. But a growing body of research is challenging that timeline. Increasingly, scientists believe that the earliest signs of celiac disease may emerge not in blood tests, or even in symptoms, but deep within the gut microbiome years before diagnosis is possible through traditional screening.
This article explores cutting-edge findings on how microbial patterns evolve long before autoimmunity fully develops, and what this could mean for early detection, prevention strategies, and anyone living with celiac disease or gluten sensitivity.
The Microbiome: ...