First Use of Echocardiography to Assess Left Ventricular Function in Celiac Patients

Celiac.com 02/16/2015 - Celiac is predominantly a disease of the small intestine characterized by chronic malabsorption in genetically susceptible individuals who ingest grains containing. gluten, such as wheat, barley, and rye.

Using strain and strain rate echocardiography imaging, a research team set out to assess left ventricular function in patients with celiac disease.

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The research team included S. Cenk, D.B. Aylin, A. Fatma Ebru, A.B. Nihal, Ö.S. Sevil, B. Serdal, B. Emine, A. Hüseyin, K. Telat, D. Tahir, E. Osman, and B. Engin. For their study, the team included twenty celiac patients and twenty healthy control subjects. They assessed left ventricle systolic and diastolic functions using standard 2-dimension, M-mode, conventional Doppler echocardiography. They obtained strain and strain rate parameters for 8 segments of the left ventricle.

They found no significant differences between patients and controls regarding left ventricle function as assessed by 2-dimensional, M-mode, conventional Doppler.

Initially, differences between strain rate values did not reach statistical significance, but when strain and average strain values were considered together, statistically significant differences emerged between the groups. For the first time a research team has been able to determine the subclinical effect of celiac disease on left ventricular systolic function by using strain echocardiography imaging.

Their success shows the potential value of assessing cardiac involvement in celiac patients using these echocardiographic techniques.

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