Celiac.com 10/18/2017 - Celiac disease is a chronic inflammatory disease of the small intestine mucosa due to permanent intolerance to dietary gluten.
A team of researchers recently set out to clarify the role of small intestinal epithelial cells in the immunopathology of celiac disease, especially the influence of celiac disease-associated bacteria.
The research team included G Pietz, R De, M Hedberg, V Sjöberg, O Sandström, O Hernell, S Hammarström, and ML Hammarström. They are variously affiliated with the Department of Clinical Microbiology, Immunology, and the Department of Clinical Sciences and Pediatrics at Umeå University, in Umeå, Sweden.
The team collected duodenal biopsies from children with active celiac disease, treated celiac disease, and a group of clinical contr...

Celiac.com 10/29/2018 - Researchers Emma L. Smith with UCB Pharma Ltd., Slough, United Kingdom, and Mark Peakman from the Department of Immunobiology, King’s College London, London, United Kingdom recently set out to catalog clinical advances in peptide immunotherapy for Type 1 diabetes.
Autoimmune and allergic diseases occur when a person’s body has an incorrect immune response to an antigen from the person’s own body, or to an innocuous antigen from outside the body. This triggers a pathogenic T-cell response which causes damage to certain tissues and organs. In Type 1 diabetes, this process results in the destruction of the insulin-secreting β cells, which leads to permanent need for recombinant insulin to make up for the loss. 
The best way to restore immune homeostasi...

Celiac.com 08/08/2019 - A strict gluten-free diet is the only currently accepted treatment for celiac disease. Current treatment guidelines for celiac disease recommend regular dietary interviews and blood tests to gauge dietary adherence. However, those guidelines might not be doing the job. 
A team of researchers recently set out to see if fecal gluten immunogenic peptides might help support the diagnosis, and determine the adherence to the gluten-free diet in celiac children.
The research team included Isabel Comino, Verónica Segura, Luis Ortigosa, Beatríz Espín, Gemma Castillejo, José Antonio Garrote, Carlos Sierra, Antonio Millán, Carmen Ribes-Koninckx, Enriqueta Román, Alfonso Rodriguez-Herrera, Jacobo Díaz, Jocelyn Anne Silvester, Ángel Cebolla, and Carolina Sousa. Th...