Celiac.com 09/20/2021 - People with celiac disease face an increased risk of death, in part due to cancer. Most studies investigating this cancer risk involved patients diagnosed before widespread increases in celiac disease diagnosis rates and access to gluten-free food. A team of researchers recently conducted a population-based study to assess the risk of cancer for people with celiac disease.
For their study, the team used the Epidemiology Strengthened by histoPathology Reports in a Swedish cohort to gather data from all celiac disease patients in Sweden, with celiac disease defined as duodenal/jejunal villus atrophy. 
They then matched each patient by age, sex, and county to five or fewer control subjects. Then, following patients from diagnosis until first cancer, o...

Celiac.com 02/28/2022 - Immune regulation is important for carcinogenesis; however, the cancer risk profiles associated with immune-mediated diseases, like celiac disease, are not well understood.
A team of researchers recently set out to assess the profiles of cancer risk associated with 48 immune-mediated diseases with the risk of total and individual cancers. They also assessed the prospective association of organ-specific immune-mediated diseases with the risk of local and extra-local cancers.
The research team included Ming-ming He, MD; Chun-Han Lo, MD, MPH; Kai Wang, MD, PhD; Georgios Polychronidis, MD; Liang Wang, MD; Rong Zhong, PhD; Markus D. Knudsen, PhD; Zhe Fang, MD; and Mingyang Song, MD, ScD.
For their prospective cohort study, the team used data from...

Celiac.com 05/01/2023 - Celiac disease is a condition that affects millions of people worldwide. Celiac disease is an immune-mediated enteropathy triggered by gluten, a protein found in wheat and related grains. For people with celiac disease, eating gluten can lead to a range of symptoms and damage to the small intestine. 
The only effective treatment for the disease is a strict gluten-free diet, which allows the intestines to heal and prevents further complications. However, recent research has shed light on the potential dangers of having celiac disease: the danger of malignant complications.
A group of researchers at the Department of Internal Medicine and Gastroenterology, University Hospital Brno, recently conducted a study examining the occurrence of malignancies in ...

Celiac.com 02/19/2024 - A recent study presented at the 2023 annual meeting of the American College of Gastroenterology has raised concerns about the increasing incidence of enteropathy-associated T-cell lymphoma (EATL) – a rare and aggressive form of T-cell, non-Hodgkin lymphoma. This alarming trend has prompted researchers to explore the possible connection between EATL and celiac disease, shedding light on the risks faced by individuals with this autoimmune condition.
Lead investigator Dr. Isabel Hujoel, Clinic Director of the Celiac Disease Center at UW Medical Center, Seattle, highlighted the strong association between EATL and celiac disease. While EATL is rare, most cases are observed in patients with celiac disease, suggesting a potential link between the two conditions. ...