The Provocation Test in Children with Cow-Milk Protein and Gluten Intolerance: Evaluation of the Clinical Response and Lesions in the Mucous Membrane of the Small Intestine

TI- Proba prowokacyjna u dzieci z nietolerancja biaLek mleka krowiego i glutenu: ocena reakcji
klinicznych i zmian w bLonie sluzowej jelita cienkiego.
AU- Kaczmarski M
CS- Kliniki Chorob Zakaznych Dzieci AM w BiaLymstoku.
JN- Pol Tyg Lek; 45 (8-9) p161-5
PY- Feb 19-26 1990

AB- Provocation test (re-introduction of the noxious protein) was carried out in two groups of patients: (a) with intolerance to the cow-milk proteins (41 children) treated with milk-free diet for 6-24 months, and ( with gluten intolerance (26 children) treated with gluten-free diet for 6-36 months. The following parameters were compared: type and frequency of the clinical symptoms seen in these patients prior to the introduction of allergen-free diet. Moreover, the type of observed morphological changes in the small intestine mucosa following provocation test were analyzed in the groups of 7 patients. A two-year elimination of milk from the diet produces milk tolerance in about 61% patients; clinical symptoms in the remaining children are diversified. Re-introduction of gluten with the diet (provocation test) produces recurrence of gluten intolerance in 96% of children treated with gluten-free diet for 2-3 years. Recurrence of the disease was accompanied by the atrophy of the intestinal villi.