Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):
  • Join Our eNewsletter:
    Support Our Content
    eNewsletter
    Donate

8 Years after celiac disease diagnosis I now have elevate liver function tests. What might this indicate?


Eileen13

Recommended Posts

Eileen13 Rookie

I was diagnosed with celiac disease in 2008.  I have had a positive result since going gluten-free, with excellent health and perfect annual blood work.  However, I just had my annual physical and lab work and my doctor just called to tell me that several liver function tests are significantly elevated (more than doubling since last year, and all outside the normal range now).  Of course I am anxious as I await now a liver ultrasound and appt with a gastroenterologist to discuss potential liver-related problems.

Has anyone here experienced liver damage or liver disease as a result of having celiac disease.  Or, could this indicate yet another autoimmune disease coming on?  Please share and advise!

Thanks!

ALT was 23 last year, now 58

AST was 24 last year now 29 (not significant and still within normal range)

GTT was 53 last year (and only 17 the prior year), now 166 (normal range is >60)

ALP was 73 last year and now is 195 (normal range is >117)


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



TexasJen Collaborator
1 hour ago, Eileen13 said:

I was diagnosed with celiac disease in 2008.  I have had a positive result since going gluten-free, with excellent health and perfect annual blood work.  However, I just had my annual physical and lab work and my doctor just called to tell me that several liver function tests are significantly elevated (more than doubling since last year, and all outside the normal range now).  Of course I am anxious as I await now a liver ultrasound and appt with a gastroenterologist to discuss potential liver-related problems.

Has anyone here experienced liver damage or liver disease as a result of having celiac disease.  Or, could this indicate yet another autoimmune disease coming on?  Please share and advise!

Thanks!

ALT was 23 last year, now 58

AST was 24 last year now 29 (not significant and still within normal range)

GTT was 53 last year (and only 17 the prior year), now 166 (normal range is >60)

ALP was 73 last year and now is 195 (normal range is >117)

Liver enzymes can be tricky.... They can go up just because of celiac, but if you are on a strict gluten-free diet and your antibodies are negative, that seems unlikely.

The gluten-free diet is very high is simple carbohydrates which can lead to fatty liver (steatohepatosis) which is the most common cause of elevated liver enzymes in the US.

Also, alcohol, drugs, hepatitis, supplements, and medications.  Sometimes they go up temporarily and come down and no one really knows why.  Make sure to write down all of your supplements, vitamins etc and show them to the GI doc.

Good luck!

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - Stegosaurus replied to HectorConvector's topic in Related Issues & Disorders
      349

      Terrible Neurological Symptoms

    2. - knitty kitty replied to HectorConvector's topic in Related Issues & Disorders
      349

      Terrible Neurological Symptoms

    3. - Aretaeus Cappadocia replied to Irishgirl5's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Digestive symptoms yet negative celiac screening

    4. - Scott Adams replied to Russ H's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      1

      Fiber-Metabolizing Bacteria Could Boost Gut Health in Celiac Disease

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,995
    • Most Online (within 30 mins)
      10,442

    Jody Booker
    Newest Member
    Jody Booker
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • Stegosaurus
      I've been following a low carbohydrate Keto AutoImmune Protocol diet.  It's all I can handle.  I'm so excited to learn about thiamine from you.  The benfotiamine should arrive today.  I sure hope it's my missing piece!!!
    • knitty kitty
      I respectfully disagree, @Scott Adams.   Thiamine deficiency (and deficiencies in other B vitamins) can cause unintentional weight loss.  The body will use stored fat and muscle to provide energy in thiamine deficiency.  This results in muscle wasting, fat loss, fatigue, and difficulty putting on muscle mass.  Using stored fat and muscle for energy requires less thiamine than the amount of thiamine required to process carbohydrates.  Thiamine deficiency causes gastrointestinal Beriberi, a localized thiamine deficiency in the digestive tract, which results in dysbiosis, inflammation, and abdominal pain.  Carbohydrates can remain undigested in the intestinal system, which bacteria feed on, encouraging SIBO, and prompting dysbiosis, leaky gut, and inflammation.  Following a low carbohydrate Keto diet, like the AutoImmune Protocol diet, can help because it removes excess carbohydrates that the bacteria feed on.  SIBO can cause weight gain due to inflammational edema of the intestines (water retention in the tissues of the intestines), gas, and slowed transit times.  SIBO bacteria can absorb nutrients from your food before you can, resulting in additional deficiencies of other B vitamins and nutrients.   Thiamine deficiency is corrected with high dose Thiamine Hydrochloride, Benfotiamine and/or Thiamine TTFD (tetrahydrofurfuryl disulfide).  High dose thiamine in the form Benfotiamine has been shown to promote intestinal healing.  It improves "leaky gut".  High dose Benfotiamine will improve the gut microbiome in favor of beneficial bacteria.  Thiamine TTFD is beneficial for neurological issues.  Thiamine TTFD improves brain function and is beneficial for mental health issues such as depression and anxiety, and other neurological problems like Ataxia and Brain Fog.    Methylated (activated) B Complex vitamins help correct Thiamine deficiency because all eight B vitamins work together.  Vitamin C and the four fat soluble vitamins (A, D, E, and K) are needed as well.  Minerals like Magnesium, Calcium, Iron,  Potassium, and others may need to be supplemented as well.  Thiamine and Magnesium make life sustaining enzymes together.   Supplementing with high doses of Thiamine and other water soluble B vitamins will lower pain and inflammation, improve fatigue, improve muscle mass gain, as well as regulate the intestinal microbiome!  So, @Stegosaurus, you can get healthier while improving gut dysbiosis at the same time! References: Thiamine, gastrointestinal beriberi and acetylcholine signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/ Dietary Vitamin B1 Intake Influences Gut Microbial Community and the Consequent Production of Short-Chain Fatty Acids https://pmc.ncbi.nlm.nih.gov/articles/PMC9147846/
    • Aretaeus Cappadocia
      You may know this already, but in addition to what you've described, you may also want to get a genetic test. About 1/3 of people have one of the genetic markers that are necessary (but not sufficient) for getting celiac. If your son is one of the 2/3 of people that don't have the marker then it is almost certain he does not have celiac. (The genetic test won't tell you if he has celiac, it can only tell you whether or not he is susceptible to getting celiac.)
    • JennMitchell79
    • Scott Adams
      That is really interesting, especially because it points to how the gut microbiome may still stay altered in celiac disease even after going gluten-free. The idea that a fiber like inulin could help feed beneficial bacteria and reduce inflammation is encouraging, although I imagine some people with celiac disease or other gut issues might still need to introduce it carefully depending on tolerance. It definitely feels like an area worth watching, because anything that could help support healing beyond just avoiding gluten would be valuable.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.