Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

I know this is very common, but help with test results please?

MerZ

Recommended Posts

MerZ Rookie
MerZ
Posted

I went to a GI for my digestive issues, never thinking it could be celiac. He didn't either, but ordered some bloodwork including the celiac screens just in case. We were both shocked when one of the markers was positive! I'm going for an endoscopy in a few weeks but asked for a copy of the labs, and I'm wondering if anyone has seen labs like this and gotten a positive diagnosis, or what else it could mean?

Deamidated gliadin IgA - 3

Deamidated gliadin IgG - 3

tTG IgA - <2

TtG IgG - 27

Endomysial antibody  - negative

Total IgA - 164

The TtG IgG is clearly positive, but the others are confusing. Also just to note, my white blood cell was slightly high (0.5) and my alkaline phosphatase was high (120). My TSH was normal. 

Thanks!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


ironictruth Proficient
ironictruth
Posted
3 hours ago, MerZ said:

I went to a GI for my digestive issues, never thinking it could be celiac. He didn't either, but ordered some bloodwork including the celiac screens just in case. We were both shocked when one of the markers was positive! I'm going for an endoscopy in a few weeks but asked for a copy of the labs, and I'm wondering if anyone has seen labs like this and gotten a positive diagnosis, or what else it could mean?

Deamidated gliadin IgA - 3

Deamidated gliadin IgG - 3

tTG IgA - <2

TtG IgG - 27

Endomysial antibody IgA - 164

 

The TtG IgG is clearly positive, but the others are confusing. Also just to note, my white blood cell was slightly high (0.5) and my alkaline phosphatase was high (120). My TSH was normal. 

Thanks!

You are on the right course. What was the lab range for EMA? 

Might also look at the liver with a high Alk Phos and positive TTG  if the biopsy does not show celiac. I assume your ALT and AST were done?  How high was the Alk Phos? 

Do not worry too much yet It will drive you nuts!

MerZ Rookie
MerZ
Posted
  • Author
6 minutes ago, ironictruth said:

You are on the right course. What was the lab range for EMA? 

Might also look at the liver with a high Alk Phos and positive TTG. I assume your ALT and AST were done? 

Thanks for your response! The range was 87-352. Not sure about ALT and AST, I'll have to look it over again. 

ironictruth Proficient
ironictruth
Posted
1 minute ago, MerZ said:

Thanks for your response! The range was 87-352. Not sure about ALT and AST, I'll have to look it over again. 

They may not  have run those tests. They are liver enzymes, I'm just wondering if you happen to know if they were done fairly recently. If not, it may be good to inquire. 

Keep us posted! 

MerZ Rookie
MerZ
Posted
  • Author
Just now, ironictruth said:

They may not  have run those tests. They are liver enzymes, I'm just wondering if you happen to know if they were done fairly recently. If not, it may be good to inquire. 

Keep us posted! 

I had a baby 6 months ago, and I am a high risk pregnancy due to cardiac history, so I get full panels done multiple times, including kidney and liver enzymes. Never had any abnormal results. 

RMJ Mentor
RMJ
Posted

Might the EMA (endomysial antigen) be 1:64?  Usually the EMA is reported in that format. It is a measure of how far they can dilute your blood and still get a positive result. 1:64 would typically be a positive for the EMA, the range does not vary a lot from lab to lab.  Does your lab report onclude the normal ranges?  

It is unusual for the tTG IgA to be negative and the EMA IgA to be positive, they are thought to be looking at the same antibodies.

Please keep eating gluten until your endoscopy to ensure an accurate result.

MerZ Rookie
MerZ
Posted
  • Author
2 minutes ago, RMJ said:

Might the EMA be 1:64?  Usually the EMA is reported in that format. It is a measure of how far they can dilute your blood and still get a positive result. 1:64 would typically be a positive for the EMA, the range does not vary a lot from lab to lab.  Does your lab report onclude the normal ranges?  

It is unusual for the tTG IgA to be negative and the EMA IgA to be positive, they are thought to be looking at the same antibodies.

Please keep eating gluten until your endoscopy to ensure an accurate result.

Nope, it says "negative, 164"

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


RMJ Mentor
RMJ
Posted

87 to 352 is not in the typical format for an EMA (endomysial antigen) normal range.  It looks more like the normal range for total IgA.

MerZ Rookie
MerZ
Posted
  • Author
Just now, RMJ said:

87 to 352 is not in the typical format for an EMA (endomysial antigen) normal range.  It looks more like the normal range for total IgA.

I'm trying to upload the picture I have, I need to resize it, hold on. 

RMJ Mentor
RMJ
Posted

I see you were writing your response as I was writing mine.  That is an unusual way to report.  I hope you get clearcut results with your endoscopy.

RMJ Mentor
RMJ
Posted

I await your photo!

MerZ Rookie
MerZ
Posted
  • Author

bloodwork.webp

MerZ Rookie
MerZ
Posted
  • Author

I just realized I was reading that wrong wasn't I? Two different things. Well I feel silly. 

RMJ Mentor
RMJ
Posted

Yes you were but that's ok, sometimes the layout of lab reports can make them quite confusing, Your EMA IgA is negative and your total IgA is in the normal range (meaning your celiac specific IgA tests are valid).  It is quite possible to have celiac with only one of the blood tests being abnormal.

Be sure to let us know the results of your endoscopy when you have it!  

MerZ Rookie
MerZ
Posted
  • Author
Just now, RMJ said:

Yes you were but that's ok, sometimes the layout of lab reports can make them quite confusing, Your EMA IgA is negative and your total IgA is in the normal range (meaning your celiac specific IgA tests are valid).  It is quite possible to have celiac with only one of the blood tests being abnormal.

Be sure to let us know the results of your endoscopy when you have it!  

I will, thanks!

I'm definitely symptomatic, and that IgG number seems pretty high, so post endoscopy I'm thinking going gluten free is probably the best option either way. 

ironictruth Proficient
ironictruth
Posted

Good lord! A new baby after a high risk pregnancy and now this! 

I hope you are getting plenty of rest and some down time for yourself. 

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. yellowstone
      - yellowstone posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      0

      Cold/flu or gluten poisoning?

      Cold/flu or gluten poisoning? Hello. I've had another similar episode. I find it very difficult to differentiate between the symptoms of a cold or flu and those caused by gluten poisoning. In fact, I don't know if my current worsening is due to having eaten something that disagreed with me or if the cold I have has caused my body, which is hypersensitive...
    2. Churro
      - Churro replied to Churro's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      17

      Celiac disease symptoms

      I'm no longer dealing with constipation. I got my liver test last month and it was in normal range. Two years ago I did have a vitamin D deficiency but I'm know taking vitamin D3 pills. Last month I got my vitamin D checked and it was in normal range. I don't believe I've had my choline checked. However, I do drink almond milk eat Greek yogurt on a daily...
    3. Wheatwacked
      - Wheatwacked replied to Churro's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      17

      Celiac disease symptoms

      Non-Celiac Gluten Sensitivity (NCGS) can be associated with low ferritin and iron deficiency. Once Celiac Disease (1% of the population affected) has been ruled out by tests the next step is to check for Non Celiac Gluten Sensitivity (10% of the population affected) by eliminating gluten for a trial period, then re-introduce Gluten Challange. Have...
    4. Churro
      - Churro replied to Churro's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      17

      Celiac disease symptoms

      Thanks for your input.
    5. trents
      - trents replied to Churro's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      17

      Celiac disease symptoms

      If you have hemorrhoids 1x weekly I don't see how you have time to heal from one episode before you experience another one, unless each one is a very minor event. Have you consulted a physician about your hemorrhoid issue? It's not normal to be having an episode every week unless it is really one episode that is not completely healing between weekly...
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,063
    • Most Online (within 30 mins)
      7,748
    JTL1976
    Newest Member
    JTL1976
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • yellowstone
      Cold/flu or gluten poisoning?

      By yellowstone · Posted

      Cold/flu or gluten poisoning? Hello. I've had another similar episode. I find it very difficult to differentiate between the symptoms of a cold or flu and those caused by gluten poisoning. In fact, I don't know if my current worsening is due to having eaten something that disagreed with me or if the cold I have has caused my body, which is hypersensitive, to produce symptoms similar to those of gluten poisoning.        
    • Churro
      Celiac disease symptoms

      By Churro · Posted

      I'm no longer dealing with constipation. I got my liver test last month and it was in normal range. Two years ago I did have a vitamin D deficiency but I'm know taking vitamin D3 pills. Last month I got my vitamin D checked and it was in normal range. I don't believe I've had my choline checked. However, I do drink almond milk eat Greek yogurt on a daily basis. 
    • Wheatwacked
      Celiac disease symptoms

      By Wheatwacked · Posted

      Non-Celiac Gluten Sensitivity (NCGS) can be associated with low ferritin and iron deficiency. Once Celiac Disease (1% of the population affected) has been ruled out by tests the next step is to check for Non Celiac Gluten Sensitivity (10% of the population affected) by eliminating gluten for a trial period, then re-introduce Gluten Challange. Have you been supplementing Iron? How are your liver enzymes? Low levels of ferritin indicate iron deficiency, while  59% transferrin saturation indicates high iron levels.  Possibly indicating Fatty Liver Disease.  Choline is crucial for liver health, and deficiency is a known trigger for Non-Alcoholic Fatty Liver.  Some experts say that less than 10% eat the the Food and Nutrition Board established Adequate Intake that are based on the prevention of liver damage. Severe constipation and hemorrhoids may be linked to a bile or choline deficiency.  "Ninety-five percent of phospholipids (PLs) in bile is secreted as phosphatidylcholine or lecithin."  Fatty acid composition of phospholipids in bile in man   Deficiency of these bile salts causes the bile to get thick. Some people with Celiac Disease are misdiagnosed with Gall Bladder bile issues.  Removal of the gallbladder provides only temporary relief. Whether or not celiac disease or NCGS are your issues you need to look at your vitamin D blood level.   
    • Churro
      Celiac disease symptoms

      By Churro · Posted

      Thanks for your input. 
    • trents
      Celiac disease symptoms

      By trents · Posted

      If you have hemorrhoids 1x weekly I don't see how you have time to heal from one episode before you experience another one, unless each one is a very minor event. Have you consulted a physician about your hemorrhoid issue? It's not normal to be having an episode every week unless it is really one episode that is not completely healing between weekly flareups.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.