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Celiac Panel Results

KM49
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KM49 Newbie
KM49
Posted

Hello, I just got my blood test results. I'm currently waiting for an EGD. My TTG-IGA is 4 and my DGP-IgG is 28. Both fall within the "weak positive" range. Would this be considered a positive blood test?

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cyclinglady Grand Master
cyclinglady
Posted

It seems like you are doing the right thing by getting intestinal biopsies.  Make sure your GI takes the appropriate amount and from the right locations.  Have that conversation with him or her in advance, even if it is an email. Start googling to learn more.   Above all, KEEP EATING Gluten DAILY or you will mess up results.  

KM49 Newbie
KM49
Posted
  • Author

I will be doing all of the above. I guess my question is more about what the chances are of a false positive with these weak positive results? Especially the Dgp-IgG because I have read that it is highly specific.

cyclinglady Grand Master
cyclinglady
Posted

Two positives, even weak, are probably accurate and are not false positives.  But who knows?   My GI told me I had a weak positive (just a positive on the DGP IgA).  Biopsies revealed some pretty severe damage though.  

I get it.  Denial.  That was me.  I just went in for a routine colonoscopy because I was over 50 and all my friends were getting them.  My GI ordered a complete celiac panel because I had anemia most of my life.  I did not have any GI issues.  Because of work issues, I waited seven weeks for my endoscopy.  I ate every delicious gluteny food I loved.  Like a load of sourdough a day (I am not kidding).  I kind of went overboard and I started to develop GI issues.  So, in my heart, I knew.  The biopsies really confirmed it.  There is no denying a lab report.  

But, I am happy to report that I am doing well and have healed completely!  

Even if you do get a negative biopsy report, consider the gluten free diet.  Why?  The small intestine is vast (size of tennis court) and the damage can be sporadic.  Or maybe you are just starting to develop celiac disease.

Start researching!  It can be your best defense!  

AussieMumInUSA Newbie
AussieMumInUSA
Posted

My daughter had a single weak positive blood test and there was visible damage observed when she had the endoscopy. Biopsies confirmed celiac disease. The blood results are not always a direct reflection of the degree of damage. 

cyclinglady Grand Master
cyclinglady
Posted
2 hours ago, AussieMumInUSA said:

My daughter had a single weak positive blood test and there was visible damage observed when she had the endoscopy. Biopsies confirmed celiac disease. The blood results are not always a direct reflection of the degree of damage. 

So true!  I had a recent repeat endoscopy which revealed very healthy healed  villi and my GI went in deep, my DGP IgA was persistently elevated even after a strict “Fasano” gluten-free diet.  The blood tests are good, but not perfect.  

amylea77 Newbie
amylea77
Posted

My daughter also had weak positives, but celiac was confirmed by the endoscopy. Her only outward symptom was stunted growth. It's kind of like a pregnancy test....a positive no matter how weak, is usually a positive. ?

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    • trents
      Medication

      By trents · Posted

      I don't see how cornstarch could alter the test results. Where did you read that?
    • knitty kitty
      Medication

      By knitty kitty · Posted

      For pain relief I take a combination of Thiamine (Benfotiamine), Pyridoxine B 6, and Cobalamine B12.  The combination of these three vitamins has analgesic effects.  I have back pain and this really works.  The B vitamins are water soluble and easily excreted.   Hope this helps!  Keep us posted on your results!
    • knitty kitty
      Taking Probiotics but Still Getting Sick After Gluten – Advice?

      By knitty kitty · Posted

      Welcome to the forum, @Xravith. I experienced similar symptoms before my diagnosis.  Mine were due to the loss of vitamins and minerals, essential nutrients we must get from our food.  With Celiac Disease, the intestinal lining, made up of thousands of villi, gets damaged and cannot absorb essential vitamins and minerals, especially the eight B vitamins.  The loss of Thiamine B 1 can cause muscle loss, inability to gain weight, edema (swelling), fatigue, migraines and palpitations.  Low thiamine can cause Gastrointestinal Beriberi with symptoms of nausea, abdominal pain and bloating.   Thiamine is only stored for a couple of weeks, so if you don't absorb enough from food daily, as the thiamine deficiency worsens physical symptoms gradually worsen.  If you're eating lots of carbs (like gluten containing foods usually do), you need more thiamine to process them (called high calorie malnutrition).  Thiamine works with all the other B vitamins, so if you're low in one, you're probably getting low in the others, too, and minerals like iron, magnesium, zinc, and calcium, as well as Vitamin D..  Talk to your doctor about checking for nutritional deficiencies.  Most doctors rarely recognize vitamin deficiency symptoms, especially in thiamine. Get a DNA test to see if you carry any Celiac genes.  If you do not have genetic markers for Celiac, it's probably IBS.  If you do have genetic markers for Celiac, it's probably Celiac.  I was misdiagnosed with IBS for years before my Celiac diagnosis.   Keep us posted on your progress. P. S. Deficiency in thiamine can cause false negatives on antibody tests, as can diabetes and anemia.  
    • Julie 911
      Medication

      By Julie 911 · Posted

      No she didn't because if I want to ask I have to pay 700$ for 1 hour appointment so I couldn't even ask. I read that fillers like cornstash can alter the result and tylenol contains it so that's why I tried to find someone who can answer. 
    • trents
      Medication

      By trents · Posted

      Did the GI doc give you any rational for stopping the Tylenol during the gluten challenge? I have never heard of this before and I can't imagine a good reason for it. Ibuprofen, maybe, because it is an anti inflammatory but acetaminophen?  I don't see that it would have any impact on the test results to take Tylenol.
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