Son's Enterolab Tests Came Back Negative

[e&j0304]

I just thought I would share the results we got back for Jack. I am still frustrated as to why he has such severe diarrhea. He has been gluten free for a week or so as we were waiting for these test results, but it hasn't made a difference. I guess I don't know what to do now. He also has two totally different genes than Ella has. She had a double DQ-1 (0602, 0604). I guess that surprises me.

I know critics of enterolab think that they give everyone a positive, so I guess we can all know that that's not true now. I don't know where to go from here for Jack....

Here are the results.

Gluten Sensitivity Testing

Fecal Antigliadin IgA 8 Units (Normal Range <10 Units)

Fecal Antitissue Transglutaminase IgA 6 Units (Normal Range <10 Units)

Microscopic Fecal Fat Score: 25 Units (Normal Range < 300 Units)

HLA-DQ Gene Molecular analysis: HLA-DQB1*0302, 0501

Food Sensitivity Testing

Fecal anti-casein (cow's milk) IgA antibody 5 Units (Normal Range <10 Units)

Fecal anti-ovalbumin (chicken egg) IgA antibody Units (Normal Range <10 Units)

Fecal Anti-Saccharomyces cerevisiae (dietary yeast) IgA Units (Normal Range <10 Units)

Fecal Anti-Soy IgA Units (Normal Range <10 Units)

(Note: Any fields left blank means that the test was not ordered.)

The level of intestinal IgA antibodies to gliadin was below the upper limit of normal, and hence there is no direct evidence of gluten sensitivity from this test. However, because 1 in 500 people cannot make IgA at all, and rarely, some people can still have clinically significant reactions to a food antigen despite the lack of a significant intestinal/fecal antibody reaction (because the reactions primarily involve T cells), if you have any syndrome or symptoms associated with gluten sensitivity, it is recommended that you try a strict gluten free diet for 6-12 months despite a negative test.

HLA gene analysis reveals that you have a genotype containing the main gene that predisposes to gluten sensitivity and celiac sprue: HLA-DQB1*0201 (HLA-DQ2) and/or HLA-DQB1*0302 (HLA-DQ8).

[Merika]

Have you done the standard blood test on him?

merika

[gf4life]

I assume both of your children have both parents in common, and that is why it surprises you, right? If that is the case, then it means that both you and your spouse carry the genes. One of you would have 0302 & either 0602, 0604, and the other would have 0501 & the other DQ1 gene...

So if you are not already on the gluten-free diet, then you should certainly watch yourselves for symptoms.

You son could have diarrhea from something else, or he could be IGA deficient (as the enterolab results are hinting at), or he could just not be producing enough antibodies due to his age, but certainly enough to cause problems...sorry, I know that doesn't help much.

You could try the diet for a longer amount of time. Some people take longer on the diet to get relief from symptoms. Also babies are notorious for putting everything in their mouths and he could be getting glutened accidentally. It seemed like I was cleaning up gluten crumbs for months after all of us went gluten-free. They were EVERYWHERE and here I was thinking my house was clean! Not to mention I had to watch EVERYONE who came in contact with my kids, since they would offer food to my kids, which almost always contained gluten. People still offer those foods, but I have my kids trained to "just say NO THANK YOU". My kids were older than yours, but it is never too early to start their "training". I remember when they were babies and anytime relatives/friends came over the kids just always seemed to have crackers, cookies, pizza crust, etc. that they were eating/teething on and they didn't get them from me! For a while they even had to stop eating food offered by my husband. He glutened my 4 year old too many times, before I finally told her not to eat ANY food from daddy until mommy says it is okay. Over the years he has gotten much better with that, and so have the kids. They are their best advocates, next to mom of course.

BTW, my kids have an assortment of 3 different genes. All three kids are different from each other. We can tell which genes my husband carries because of the way the kids genes are.(see my signature for the specific genes) My husband is not on the diet, but at least admits he carries the genes. If he ever gets sick enough I might be able to convince him to be tested and try the diet. He eats mostly gluten-free at home, but away from home he eats plenty of gluten.

[e&j0304]

Thank you both for taking the time to respond. We did not do standard blood testing on Jack because we felt that at his age it probably wouldn't come back positive. We did have the blood testing on our daughter and it came back negative although I'm not sure they ran all of the tests. She was about 2.5 years old at that time. We then decided to just try going gluten-free for her and had AMAZING results within 4 days. We had her stool tested through enterolab after she had already been gluten-free for about 1.5 months and her results were postive that she was gluten intolerant.

We have decided that for now we are going to take Jack off of soy milk and just give him cows milk as well as keep him gluten free. He was only drinking soy because that is what my daughter drinks and it was around so we gave it to him. We then tried cow's milk and he didn't like it so we stuck with soy. We are now giving him cow's milk with chocolate powder in it so he'll drink it. If the diarrhea clears up then we can give him some gluten and see what happens. Maybe this was all just a reaction to soy milk?

He has been totally on cow's milk for a day now so we'll see. He's still having diarrhea, but obviously it's too soon to make a difference there.

Anyway, thanks for trying to help!

Shannon

[taweavmo3]

Hope you can get the diarrhea to stop soon.....I'm sure you'll figure out what the culprit is. We've had great success with taking Ben off of soy milk, he has completely normal bm's now. His mood has improved, as well as his speech . I'm one happy momma! The weird thing is, now that we took him off soy, he has been tolerating small amounts of dairy. I really don't get it...but it's a good thing.

Good luck and keep us posted!

[gf4life]

Definitely let us know how he is doing.

It certainly could have been the soy milk. We took our kids off dairy for over a year. All of us came back casein intolerant on the interolab tests, and our pedi. GI doctor supported me taking them off dairy, but told me to watch them for soy intolerance if we gave them soy milk. He said you would know pretty quickly because they would get a stomachache and diarrhea! My kids didn't like the taste of soy milk and we choose almond milk instead. We have successfully added dairy back in for over 9 months now with no adverse effects.

I hope Jack feels all better soon.

God bless,

Mariann