2nd Opinion?

[slpinsd]

For 8 years, I've had digestive issues that became remarkably bad after ingesting pizza or pasta. I recently had bloodwork that was IgG positive. My other numbers were AGA IgA 15, tTg IgA 13. However, my total IgA was 108 so I'm told that that is on the low end, and can bring down the IgA's a little, and would be higher if I produced more IgA. Also found were a severe vitamin B12 deficiency, H Pylori, food intolerances to eggs, adrenal exhaustion, dairy, sugar, and many fruits and others. Given a recent rapid unexplainable weight loss, I had a biopsy. The GI stated that she saw "Mild flattening of the villi noted- of unclear significance". So, for 1 week I was pretty sure the biopsy was going to be postitive. But, it came back negative, with no histological changes. Does anyone know if you have gluten intolerance but no tissue damage, could I still have malabsorption causing weight loss? I have ordered Enterolab genetic testing. Some have mentioned getting a second opinion on the biopsy. So far, I have had a remarkable response to the gluten-free diet. My unrelenting acid reflux, to the point of not being able to breathe after eating, vanished after 5 days. Should I wait for the genetic testing to look for a second opinion? I would not be curious about the 2nd opinion if the Dr. had not remarked on seeing flattening of the villi.

[jerseyangel]

If the dr. SAW flattening of the villi, and given your symptoms and given the fact that you feel remarkably better on the gluten-free diet--I would say you have it and if it were me, I would just keep on being gluten-free and getting healthy. It could be that the biopsy was taken where there was no damage, or the person who read the biopsy was not experienced with Celiac. Since you ordered the genetic testing, do that--and then deceide if you even need a second opinion.