Ttg Iga levels rising slightly

[Randommuwa]

I've had 3 celiac panels done and my levels seem to be rising slightly, does this mean anything? I've had a negative biopsy and Celiacs is still only considered "probable" at the time. 

 

First Ttg-iga: 5.7 (Dated 5/27/21)

Normal range: <4.0

Weak positive (4.0-10.0)

 

Second Ttg-iga: 5.8 (Dated 8/4/21)

Normal range: <4.0

Weak positive (4.0-10.0)

 

Third Ttg-iga: 6 (Dated 10/26/21)

Normal range: 0-3

 

[RMJ]

If run at the same lab, there probably isn’t much difference between a 5.7 and a 5.8.  If you run a sample from the same test tube twice you could get that type of result.

Was the October sample run at the same lab?  The normal range is stated differently and the result doesn’t include the first decimal place.   When tests are made by different manufacturers the numbers can’t be compared because the units aren’t absolute/standardized.

[Scott Adams]

You have 3 "weak" positive tests for celiac disease. Just one could mean that you have it. Were you eating 2 slices of wheat bread daily in the 6-8 weeks leading up to each test? This is the protocol, and if you were not, and were eating a low gluten diet it could explain these results.

To me your results mean that you likely have celiac disease and need a 100% gluten-free diet for life, but discuss this with your doctor and consider getting a biopsy (you need to eat 2 slices of bread daily for 2 weeks before this).

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