Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

DQ2.2 Homozygous

BushbabyLou
 Share

Recommended Posts

BushbabyLou Rookie
BushbabyLou
Posted

Hi, 

 

can someone please help me to decipher my nutrahacker results? I have also done a Randox gene test which told me I have HLQ-DQA1*03. Does this and my nutrahacker results suggest I may have a disposition to celiac disease? I have my endoscopy next week to determine whether I actually have it. 
 

TIA46305875-F14A-4151-891F-F65DC291F201.webp.5b9ddff7bb7ddc7b8f17bc37b6a9ae16.webp

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Scott Adams Grand Master
Scott Adams
Posted

I can't read the results that are cut off below the first table, but it looks like you are positive on the very top line of the first table, the DQ2.2, is that correct? 

I am no genetic expert on your exact risk, but the company who did this test should be able to give you that info. Have you contacted them about your results?

BushbabyLou Rookie
BushbabyLou
Posted
  • Author
21 minutes ago, Scott Adams said:

I can't read the results that are cut off below the first table, but it looks like you are positive on the very top line of the first table, the DQ2.2, is that correct? 

I am no genetic expert on your exact risk, but the company who did this test should be able to give you that info. Have you contacted them about your results?

Hi, thank you for you reply. That’s what I thought. I will try contacting them but they don’t really offer a consultation service. I have my endoscopy Wednesday so might as well just wait for the results of that.

Scott Adams Grand Master
Scott Adams
Posted

Sure, have you been eating ~2 slices worth of wheat bread or equivalent for the last couple of weeks? This is required before an endoscopy for celiac disease. Let us know how it goes!

JD-FLA Contributor
JD-FLA
Posted
On 8/17/2022 at 12:18 PM, BushbabyLou said:

Hi, 

 

can someone please help me to decipher my nutrahacker results? I have also done a Randox gene test which told me I have HLQ-DQA1*03. Does this and my nutrahacker results suggest I may have a disposition to celiac disease? I have my endoscopy next week to determine whether I actually have it. 
 

TIA46305875-F14A-4151-891F-F65DC291F201.webp.5b9ddff7bb7ddc7b8f17bc37b6a9ae16.webp

I had my genetic testing done as well although the results were not quite as detailed as yours are. I did post them on this site but did not get any response. I have to assume that most do not have this testing done. Like you I was lost at what the results meant so I reached out to the online lab I used to get them done and the reply is that they are not medical doctors and cannot diagnose or interrupt the results. I did an exhausting online search and found genetic test results to be confusing. I pulled this from one of those searches...

To explain the genes that are associated with celiac disease, I've taking excerpts from About.com -

Jane Anderson's Gluten Sensitivity and Celiac Disease: Celiac Disease Genetic Testing:

"The genes that predispose you to celiac disease are located on the HLA-class II complex of our DNA, and they're known as the DQ genes. Everyone has two copies of a DQ gene - one from their mother and one from their father. There are numerous types of DQ genes, but there are two that are involved in the vast majority of celiac disease cases: HLA-DQ2 and HLA-DQ8".

HLA-DQ2

"People who have two copies of HLA-DQ2 (a very small percentage of the population) carry the highest overall risk for celiac disease. People who are HLA-DQ2 homozygous also have an increased risk for at least one type of refractory celiac disease (which occurs when the gluten-free diet doesn't seem to work to control the condition), and for enteropathy-associated T-cell lymphoma, a type of cancer that's associated with celiac disease."

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,719
    • Most Online (within 30 mins)
      7,748
    storeopinionpc
    Newest Member
    storeopinionpc
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Who's Online (See full list)

  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Rejoicephd
      Draft gluten-free ciders… can they be trusted ?

      By Rejoicephd · Posted

      @Scott Adams That's actually exactly what I ended up asking for— vodka tonic with Titos.  I saw on their website that Tito's is certified gluten-free (maybe many of the clear vodkas are, I don't know, I just happened to look up Tito's in advance). I should have actually specified the 'splash' though, because I think with the amount of tonic she put in there, it did still end up fairly sweet.  Anyway, I think I've almost got this drink order down!
    • Wends
      Inconclusive results

      By Wends · Posted

      Be interesting to see the effects of dairy reintroduction with gluten. As well as milk protein sensitivity in and of itself the casein part particularly has been shown to mimic gluten in about 50% of celiacs. Keep us posted!
    • deanna1ynne
      Inconclusive results

      By deanna1ynne · Posted

      She has been dairy free for six years, so she’d already been dairy free for two years at her last testing and was dairy free for the entire gluten challenge this year as well (that had positive results). However, now that we’re doing another biopsy in six weeks, we decided to do everything we can to try to “see” the effects, so we decided this past week to add back in dairy temporarily for breakfast (milk and cereal combo like you said).
    • Gigi2025
      How Come Gluten Didnt Bother Me In Italy

      By Gigi2025 · Posted

      Hi Christiana, Many thanks for your response.  Interestingly, I too cannot eat wheat in France without feeling effects (much less than in the US, but won't indulge nonetheless).  I also understand children are screened for celiac in Italy prior to starting their education. Wise idea as it seems my grandson has the beginning symptoms (several celiacs in his dad's family), but parents continue to think he's just being difficult.  Argh.  There's a test I took that diagnosed gluten sensitivity in 2014 via Entero Labs, and am planning on having done again.  Truth be told, I'm hoping it's the bromine/additives/preservatives as I miss breads and pastas terribly when home here in the states!  Be well and here's to our guts healing ❤️
    • Wends
      Inconclusive results

      By Wends · Posted

      Lol that’s so true! Hope you get clarity, it’s tough when there’s doubt. There’s so much known about celiac disease with all the scientific research that’s been done so far yet practically and clinically there’s also so much unknown, still. Out of curiosity what’s her dairy consumption like? Even compared to early years to now? Has that changed? Calcium is dependent in the mechanism of antigen presenting cells in the gut. High calcium foods with gluten grains can initiate inflammation greater.  This is why breakfast cereals and milk combo long term can be a ticking time bomb for genetically susceptible celiacs (not a scientific statement by any means but my current personal opinion based on reasoning at present). Milk and wheat are the top culprits for food sensitivity. Especially in childhood. There are also patient cases of antibodies normalising in celiac children who had milk protein intolerance/ delayed type allergy. Some asymptomatic. There were a couple of cases of suspected celiacs that turned out to have milk protein intolerance that normalised antibodies on a gluten containing diet. Then there were others that only normalised antibodies once gluten and milk was eliminated. Milk kept the antibodies positive. Celiac disease is complicated to say the least.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.