Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

DQ2.2 Homozygous

BushbabyLou
 Share

Recommended Posts

BushbabyLou Rookie
BushbabyLou
Posted

Hi, 

 

can someone please help me to decipher my nutrahacker results? I have also done a Randox gene test which told me I have HLQ-DQA1*03. Does this and my nutrahacker results suggest I may have a disposition to celiac disease? I have my endoscopy next week to determine whether I actually have it. 
 

TIA46305875-F14A-4151-891F-F65DC291F201.webp.5b9ddff7bb7ddc7b8f17bc37b6a9ae16.webp

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Scott Adams Grand Master
Scott Adams
Posted

I can't read the results that are cut off below the first table, but it looks like you are positive on the very top line of the first table, the DQ2.2, is that correct? 

I am no genetic expert on your exact risk, but the company who did this test should be able to give you that info. Have you contacted them about your results?

BushbabyLou Rookie
BushbabyLou
Posted
  • Author
21 minutes ago, Scott Adams said:

I can't read the results that are cut off below the first table, but it looks like you are positive on the very top line of the first table, the DQ2.2, is that correct? 

I am no genetic expert on your exact risk, but the company who did this test should be able to give you that info. Have you contacted them about your results?

Hi, thank you for you reply. That’s what I thought. I will try contacting them but they don’t really offer a consultation service. I have my endoscopy Wednesday so might as well just wait for the results of that.

Scott Adams Grand Master
Scott Adams
Posted

Sure, have you been eating ~2 slices worth of wheat bread or equivalent for the last couple of weeks? This is required before an endoscopy for celiac disease. Let us know how it goes!

JD-New to Celiac Explorer
JD-New to Celiac
Posted
On 8/17/2022 at 12:18 PM, BushbabyLou said:

Hi, 

 

can someone please help me to decipher my nutrahacker results? I have also done a Randox gene test which told me I have HLQ-DQA1*03. Does this and my nutrahacker results suggest I may have a disposition to celiac disease? I have my endoscopy next week to determine whether I actually have it. 
 

TIA46305875-F14A-4151-891F-F65DC291F201.webp.5b9ddff7bb7ddc7b8f17bc37b6a9ae16.webp

I had my genetic testing done as well although the results were not quite as detailed as yours are. I did post them on this site but did not get any response. I have to assume that most do not have this testing done. Like you I was lost at what the results meant so I reached out to the online lab I used to get them done and the reply is that they are not medical doctors and cannot diagnose or interrupt the results. I did an exhausting online search and found genetic test results to be confusing. I pulled this from one of those searches...

To explain the genes that are associated with celiac disease, I've taking excerpts from About.com -

Jane Anderson's Gluten Sensitivity and Celiac Disease: Celiac Disease Genetic Testing:

"The genes that predispose you to celiac disease are located on the HLA-class II complex of our DNA, and they're known as the DQ genes. Everyone has two copies of a DQ gene - one from their mother and one from their father. There are numerous types of DQ genes, but there are two that are involved in the vast majority of celiac disease cases: HLA-DQ2 and HLA-DQ8".

HLA-DQ2

"People who have two copies of HLA-DQ2 (a very small percentage of the population) carry the highest overall risk for celiac disease. People who are HLA-DQ2 homozygous also have an increased risk for at least one type of refractory celiac disease (which occurs when the gluten-free diet doesn't seem to work to control the condition), and for enteropathy-associated T-cell lymphoma, a type of cancer that's associated with celiac disease."

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      129,442
    • Most Online (within 30 mins)
      7,748
    Guiido79
    Newest Member
    Guiido79
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.2k
    • Total Posts
      71.7k
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • trents
      Newly diagnosed and maybe some type of protein intolerance.

      By trents · Posted

      Thanks for the clarification on the scope. This is what confused me, "gastro doc said from the biopsy there was mild atrophied villi but I know that could be from where the sample was taken and they could be gone not far away." I interpreted that to mean when the scope was done they didn't do a thorough job of checking the area that would be affected by celiac disease and were looking for other things.
    • Tedro
      Newly diagnosed and maybe some type of protein intolerance.

      By Tedro · Posted

      I already had a scope done and he said there were damaged villi. This follow up is to go over the bloodwork I already know the results to and the gastric emptying study I had done.  I won't say the burgers were not greasy but not bad. It even happens with chicken breast or tenderloin in the air fryer and that's not very fatty at all.
    • trents
      Newly diagnosed and maybe some type of protein intolerance.

      By trents · Posted

      You might be having trouble digesting meat because of the damage to your villi. But what about gallbladder problems? Were those burgers, even the turkey ones, greasy? The odd thing is the "peeing like a racehorse" after consumption. You say you have follow up GI appointment coming up. Please be aware if the GI doc wants to do an upper GI to specifically check for villous atrophy of the small bowel, the hallmark of celiac disease, going on a gluten free diet already may invalidate the results as it allows for healing to occur. 
    • Tedro
      Newly diagnosed and maybe some type of protein intolerance.

      By Tedro · Posted

      Had noticeable issues for 7 months including 3 trips to the ER for extreme discomfort. Every doc just said I had gastritis, take pepcid. This never changed a thing. Finally talked a doc into a referral to a gastroenterologist who I had to convince to do a scope and bloodwork to test for celiac among other things. It's like nobody believed me when I said I was sick. I got results back saying positive for an autoimmune disease but not which one. At that point I started a gluten-free diet based upon my own findings. The following week I check my insurance site and there's a message that I tested positive for celiacs. Never got a phone call. This was 5 weeks ago. The message said they suggest I maintain my follow up appointment which is may 19. No instructions on what to do, avoid, anything.  I am smart enough to figure this out thankfully.  So now 5 weeks into it I definitely feel an improvement. Been only eating things that say certified gluten free on the packaging.  I was eating a breakfast protein kind bar in the morning but stopped because they aren't certified gluten-free. Also it seemed I would have hard upper gi grumbles when I ate them and I just figured maybe the oats were hard to digest. one of my symptoms was a hard gi grumble that lasted for hours after eating gluten. Eggs don't seem to bother me but I only have 1 or 2. Dairy doesn't seem to bother me. 2 sundays ago I had 2 burgers with no bun. 2 patties on the grill. slice of prepackaged provolone. Half way through the second burger it hit me and I felt horrible. 2 hrs later I am peeing every half hour and up half the night. Thought maybe the small amount of seasoning I used that was gluten-free got cross contamination. This past saturday made a steak. Real butter in a clean pan and throw the steak on. 2 hrs after eating it same thing. Hard grumbles, peeing every half hour for several hours, and plain exhausted. around 6pm yesterday....gluten-free turkey burger in the air fryer. 2 hrs later peeing like a racehorse, hard grumbles in my upper gi. I'm still feeling the effects today. I tried all day to find an allergist but the soonest appointment is in August. I have an appointment with a nutritionist the first week of june.  Thinking back the worst reactions I've had  before diagnosis were general tsos which could have been breading or animal protein I guess. A fried fish sandwich. again could be Bread or protein. 2 burgers while on vacation this past winter. Also since diagnosis I made a porkchop with green beans and sweet potatoes and got the same sick which to me makes me think I'm having more of a reaction to meat or its protein than I am to gluten. gastro doc said from the biopsy there was mild atrophied villi but I know that could be from where the sample was taken and they could be gone not far away.  I'm very frustrated from going gluten free 5 weeks ago and having similar reactions to what should be clean gluten-free food like steak or turkey. I know it takes a long time to heal. I know I have celiacs from the blood work. I just wonder if there is something else going on this whole time. Has anyone had any similar experiences or have any insight? I am looking forward to my gastro appointment next week and have a list of comments and questions but i'm not getting my hopes up. I am by myself and am really struggling with all of this so I'm glad I found this community. I looked through a lot of posts and haven't really seen anything similar. Thank you all in advance.
    • Scott Adams
      Rosacea

      By Scott Adams · Posted

      You may want to go to a dermatologist to see if it might instead be dermatitis herpetiformis, which is the skin version of celiac disease. Here are some articles on Rosacea and CD:    
×
×
  • Create New...