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Histamine Intolerance

fergusminto
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fergusminto Apprentice
fergusminto
Posted

Having been diagnosed with celiac disease in 2009 I increasingly developed intolerances to certain foods and beverages like dairy, eggs, alcohol, food preservatives, tomatoes etc. haven’t had much success with doctors/dieticians here esp with current Govt cutbacks so have been doing my own research. I am sick to death of headaches during the night and always try and pinpoint exactly what has caused them eg gym work, drinks, food etc. I have finally come to the conclusion that I have a histamine problem. Everything seems to fit - a lack of DAO.

Are celiac disease and histamine intolerance related in any way? How do I “cure” it? 
Would be very grateful for advice.

 

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Rogol72 Collaborator
Rogol72
Posted
1 hour ago, fergusminto said:

Having been diagnosed with celiac disease in 2009 I increasingly developed intolerances to certain foods and beverages like dairy, eggs, alcohol, food preservatives, tomatoes etc. haven’t had much success with doctors/dieticians here esp with current Govt cutbacks so have been doing my own research. I am sick to death of headaches during the night and always try and pinpoint exactly what has caused them eg gym work, drinks, food etc. I have finally come to the conclusion that I have a histamine problem. Everything seems to fit - a lack of DAO.

Are celiac disease and histamine intolerance related in any way? How do I “cure” it? 
Would be very grateful for advice.

 

I believe Coelics are prone to developing histamine intolerance and MCAS. For me it comes down to making sure my body has all the Vitamins and Minerals it needs to heal and the cofactors needed to produce DAO. Dysbiosis plays a role in HI also. My HI has improved vastly since minimizing food and beverages high in histamine ... though this can be difficult in some cases. If I eat a meal high in histamine, I fall asleep afterwards for a few minutes ... post meal narcolepsy!!

Here's some resources I found educational and helpful.

https://www.youtube.com/watch?v=KIDBgJNIO8Y

https://www.factvsfitness.com/blogs/news/histamine-intolerance-headaches-migraines

https://www.healinghistamine.com/

 

fergusminto Apprentice
fergusminto
Posted
  • Author

Many thanks for this. I take it there are no DAO supplements available yet. My diet is already seriously restricted - I can see further restrictions will be necessary! I do take Sodium Cromoglycate (Nalcrom) but it doesn’t appear to help. Maybe I should increase the dose. Regards. 

shadycharacter Enthusiast
shadycharacter
Posted
4 minutes ago, fergusminto said:

Many thanks for this. I take it there are no DAO supplements available yet. My diet is already seriously restricted - I can see further restrictions will be necessary! I do take Sodium Cromoglycate (Nalcrom) but it doesn’t appear to help. Maybe I should increase the dose. Regards. 

I think there are DAO supplements. DAO contains copper, so make sure your not copper deficient. 

fergusminto Apprentice
fergusminto
Posted
  • Author

Thanks. I will have another search through the internet and see if I can get any here in Scotland. Regards.

knitty kitty Grand Master
knitty kitty
Posted

@fergusminto,

I found following a low histamine diet and taking certain vitamins that help break down histamine helped me.  

Here's an explanation of the low histamine diet...

https://www.verywellhealth.com/what-is-a-low-histamine-diet-4694529

And...

Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143338/

If you change your diet, your intestinal flora will change, too, eliminating undesirable bacteria that make histamine in the gut.

The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria of the gut microbiota in histamine intolerant women. A pilot study

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633985/

And...

Take a B Complex supplement and additional thiamine (benfotiamine) since the eight B vitamins help get rid of histamine, especially Thiamine.

Increased mast cell degranulation within thalamus in early pre-lesion stages of an experimental model of Wernicke's encephalopathy

https://pubmed.ncbi.nlm.nih.gov/10411347/

Thiamine will help migraines, too.  I used to have painful debilitating migraines, but they have stopped since taking high dose Thiamine.  I still get ophthalmic migraines from computer usage (caused by vitamin deficiencies affecting the optic nerve prior to Celiac diagnosis).  

Dietary intake of thiamine and riboflavin in relation to severe headache or migraine: A cross-sectional survey

https://pubmed.ncbi.nlm.nih.gov/36047917/

Vitamins are probably available in Scotland.  

fergusminto Apprentice
fergusminto
Posted
  • Author

Thanks KK! Yes vitamins are available here!

Sitting here on vacation in Dornoch with a splitting headache - I think the bedclothes must have been washed in some detergent I am intolerant to. Typical histamine reaction.

These articles are excellent so thank you for sending them over.

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Awol cast iron stomach Experienced
Awol cast iron stomach
Posted

I modified my diet for years in addition to gluten, as I had multiple food intolerances post gluten challenge. I still watch my histamine levels particularly during allergy season, as I have environmental allergies as well that can increase my histamine load.  As others mentioned I also maintain nutrition/supplementation as well. Lastly, I regularly have acupuncture to support my immune system, and histamine levels. 

Best wishes 

  • 2 weeks later...
fergusminto Apprentice
fergusminto
Posted
  • Author

Since opening this thread I have read through the responses (some great sources there, thanks) and have started taking a DAO supplement. Effects have been much better and faster than I first expected with my aches and pains, especially in my lower back much improved. I cannot say that it has helped my multi food/aroma intolerances yet but hoping! I am also going to the gym twice a week to strengthen my back and core.

Histamine intolerance has still not been confirmed by the NHS - it all takes time now thanks to U.K. Govt.

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    • Zuma888
      Hypothetical question about antibodies

      By Zuma888 · Posted

      Thank you so much.
    • knitty kitty
      Hypothetical question about antibodies

      By knitty kitty · Posted

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    • Zuma888
      Hypothetical question about antibodies

      By Zuma888 · Posted

      Thanks @Scott Adams! I guess my question now is: do the celiacs who can get away with regular contamination without villi damage as you mentioned have to be strict about cross-contamination ? 
    • Zuma888
      Hypothetical question about antibodies

      By Zuma888 · Posted

      Thank you very much @knitty kitty! I'm glad you brought up the point about histamine. I have been taking an antihistamine after meals where I don't feel so good and never knew why it helped so much. At first I thought I might have a food allergy, but I recently did a food allergy test and I actually have ZERO food allergies. Regarding your last point about the stages of grief, are you saying it's likely that I have celiac? I have Hashimoto's BTW and I know for sure that gluten causes an autoimmune response to my thyroid as my anti-TPO and anti-Tg go up and my throat feels swollen. Could the symptoms be due to that autoimmune response?
    • knitty kitty
      Hypothetical question about antibodies

      By knitty kitty · Posted

      @Zuma888, The antibodies produced in response to gluten are made in the intestines.  When the body is provoked sufficiently, the antibodies overflow out of the intestines and into the blood stream.  Once in the blood stream, the antibodies can be measured with tTg IgA tests.  Three grams of gluten per day for two weeks minimum is enough gluten to make you feel the symptoms of having been glutened, but the antibodies are not in sufficient quantity to be measured in the blood. Ten grams of gluten per day for a minimum of two weeks is required to get the anti gluten antibodies at a high enough level in the blood stream to be measured by tTg IgA tests. So, no, occasional cross contamination or (heaven forbid) intentional cheat days will not be sufficient for tTg IgA testing.  You will still be making antibodies which will still be causing inflammation and damage to the intestines and body.  Histamine is released as part of the immune response to gluten.  High histamine levels lead to food sensitivities, brain fog, and body aches.   The damage done to the gastrointestinal tract affects the absorption of essential vitamins and minerals.  Malabsorption of fats can cause changes in stools.  Insufficient absorption of vitamins and minerals can cause damage to other organs like the thyroid if it can't get enough Selenium, iodine, iron, zinc, and Thiamine.  Brain fog and fatigue can be caused by low Thiamine and other B Complex vitamins.  Vitamin D is needed to regulate the immune system.  One gene is all that's needed to develop Celiac disease.  I know a Celiac diagnosis is a change that can be difficult to get your head around.  Many people go through the five stages of grief.  One stage is "bargaining".  Sounds like you're stuck there.  Every little cheat counts to your detriment.  But sticking to a gluten free diet, makes every meal a success.   Read the comments below the article... Best wishes!  Keep us posted on your progress!
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