Help with blood test result

[gemknorodo]

Hello

I have recently had several blood tests and one of them was for celiac, I have had the following result

TG IgA level

Immunoglobulin A Level 3.06 g/L (range 0.8 - 2.8)

Is this in indicator of celiac?

My GP has marked it as borderline and said I need to make an appt to discuss it.

 

 

 

[trents]

Welcome to the forum, @gemknorodo!

In your post you actually mention two antibody tests that are commonly run when checking for celiac disease.

The first is the TG-IgA. You do not give a score for that one.

The second one is the Immunoglobulin A for which you scored 3.06. This is above the normal range. This test is also commonly known as "total IGA". What you need to know is that it is not a test that detects celiac disease per se. It is used to determine if the person being tested is IGA deficient. IGA deficiency results in inaccurate scores for the IGA tests that are used to detect celiac disease such as the TG IgA. IGA deficiency depresses the other IGA scores and so, it can cause false negatives. In your case, you are not IGA deficient so that is not an issue for you. In case you are wondering, I do not know that there is any particular significance or health risks associated with higher than normal total IGA. But that is something you can ask your physician.

Here is an article that outlines the various tests that can be run when checking for celiac disease:

There are other IGA tests that can be run when checking for celiac disease and there are also IGG tests that can be run to check for celiac disease. You might talk to your physician about having a more complete "celiac panel" run. Your physician might also want to refer you to a gastroenterologist who might do more extensive antibody panel or even an endoscopy with a biopsy to check for the damage to the small bowel lining caused by celiac disease.

May we ask what symptoms you are experiencing? What has led up to you being tested for celiac disease?

[Scott Adams]

Is it possible you overlooked the results of your tTg-IgA test results? It looks like you might have only shared with us one part of your test results. 

[gemknorodo]

I wonder if the tTG-Iga result isn't back yet as there is nothing next to that one, perhaps it takes a little longer.

 

[trents]

Sometimes that is the case but what is curious to me is the remark by your physician about being "borderline". I assume he was referring to the total IGA score but it just seems like an irrelevant remark when it is on the high side rather than being deficient.

Edited November 12, 2024 by trents

[trents]

I was wrong, however, about there being no particular health concerns associated with high total IGA: https://www.inspire.com/resources/chronic-disease/understanding-high-iga-levels-causes-impacts/

So maybe the physician's "borderline" remark is relevant to that.