Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Vaccine For Cd

debmidge

Recommended Posts

debmidge Rising Star
debmidge
Posted

Has anyone heard any more on this topic? I thought I read something recently that in 1999 some researcher somewhere (I think in UK) was working on a vaccine. Does anyone know the progress, or was I dreaming this up?

  • 2 weeks later...
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


flagbabyds Collaborator
flagbabyds
Posted

I've never heard anything about that. I dunno if I just haven't heard of it. That would be really interesting but celiac disease is genitic and if you have the gene then you have it right? I don't know how a vaccine would kill the celiac disease gene.

kejohe Apprentice
kejohe
Posted

I have heard about the research being done for a gene suppressor... or at least I think that's what they are calling it. It's supposed to act just like Lactaid does for people who are lactose intolerant. It would supress the gene that makes a celiac a celiac so that they could consume gluten without the negative effects.

I haven't heard about wether or not it will be a daily medication or something that you would only take before you consumed gluten (like taking lactaid before eating cheesecake). And I haven't heard anything new in a while, so I kind of forgot about it until I read your post.

It would be cool to have something like that available, but like most medications, it takes years of tests to determine if there are any long term side effects, and I would be really timid to try it on my son, until he is old enough to decide for himself whether or not he wants to take the risks.

flagbabyds Collaborator
flagbabyds
Posted

I thought it would be more like a shot you give to little kids so they don't develop it later in life like the chicken pox vaccine and that is why i was confused. i know someone who has already found the gene and is now testing his pill(almost in pill form) on people in the Bay Area. his name is chaitan khloslav(sp?) and he lives in Palo Alto CAlifornia.

debmidge Rising Star
debmidge
Posted
  • Author

I read about it on Celiac.com and the article was a little old. I was wondering if anyone had learned anything new about it.

debmidge Rising Star
debmidge
Posted
  • Author

The original report can be found at celiac.com, go to Site Index, the find Diagnosis Testing & Treatment, then go to Austrialians Begin Work on vaccine. The report is foom 2002. It appears that a Dr. Robert Anderson of the Nuffield Dept of Medicine, University of Oxford, Australia was working on this.

simone Newbie
simone
Posted

I don't know anything about a Celiac vaccine but there are many kinds of vaccines. I work at a company that makes gene therapeutics and from my understanding celiac disease is a lack of a proper gene that would help the body break down gluten, so the effect would have to be an enzyme/gene replacement rather than suppression.

Also, there is a connection with Celiac Disease and auto-immune disorders, meaning your body attacks it's own components. I am not sure how that directly ties into celiac disease as I am just now learning all of this. My guess is that a vaccine might have to somehow suppress the auto-immune response???

Anyone else have a clue? But don't take my word for it. I am just supposin'. I will look into that article and see what they indicate.

Simone

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


debmidge Rising Star
debmidge
Posted
  • Author

I am anxious to know how far they are into the vaccine development and testing stage. I am afraid that with such little "press/media" coverage there is on celiac disease that Oxford could have a working vaccine without us knowing until it's been out there for years. Keep in mind that in the event that Oxford (Austrailia) has a vaccine, we woundn't have it here until that lab got FDA approval to sell it in the USA. That could add years onto it's distribution here. Celiacs would probably have to fly to Austrailia, or UK or possibly the islands in the Carribean which are owned by UK (Jamacia?) in order to get this vaccine and they'd have to pay cash $$ as insurance doesn't cover treatments outside of the USA yet.

simone Newbie
simone
Posted

Yes, the FDA does take a long time to approve things. It is good in that long term effects can be observed but, coming from the other side, a company that wants to get products approved, there is a TON of paperwork. :blink:

Also want to confirm that from the vaccine article the process does indicate an immune system suppression with some fancy T-cell manipulation. Some day hopefully. . . :D

Keep your fingers crossed!

Simone

kejohe Apprentice
kejohe
Posted

Now that I think about it, Simone, your right about celiac being a lack of the correct gene to digest the gluten protiens so it must have been a response supressant that I read about. My nutrition and food science professor gave me the article about it after she found out my son had celiac, but it was almost 2 years ago that I heard of it, and nothing new since.

In any case, if it's trueand it really is being developed that would be great for

everyone.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. knitty kitty
      - knitty kitty replied to tiffanygosci's topic in Coping with Celiac Disease
      13

      New Celiac Mama in My 30s

      @tiffanygosci, Thiamine deficiency is a thing in pregnancy for "normal" people, so it's exponentially more important for those with celiac disease and malabsorption issues. I studied nutrition before earning a degree in Microbiology because I was curious what the vitamins were doing inside the body. See my blog. Click on my name to go to my page...
    2. tiffanygosci
      - tiffanygosci replied to tiffanygosci's topic in Coping with Celiac Disease
      13

      New Celiac Mama in My 30s

      Thank you for sharing all of this, Knitty Kitty! I did just want someone to share some commonality with. I did not know This one Deficiency was a thing and that it's common for Celiac Disease. It makes sense since this is a disorder that causes malabsorption. I will have to keep this in mind for my next appointments. You also just spurred me on to make that...
    3. RMJ
      - RMJ replied to Riley.'s topic in Introduce Yourself / Share Stuff
      4

      Outgrow celiac?

      I think your initial idea, eat gluten and be tested, was excellent. Now you have fear of that testing, but isn’t there also a fear each time you eat gluten that you’re injuring your body? Possibly affecting future fertility, bone health and more? Wouldn’t it be better to know for sure one way or the other? If you test negative, then you celebrate and g...
    4. knitty kitty
      - knitty kitty replied to Riley.'s topic in Introduce Yourself / Share Stuff
      4

      Outgrow celiac?

      @Riley., Welcome to the forum, but don't do it! Don't continue to eat gluten! The health problems that will come if you continue to eat gluten are not worth it. Problems may not show up for years, but the constant inflammation and nutritional losses will manifest eventually. There's many of us oldsters on the forum who wish they'd been diagnosed...
    5. knitty kitty
      - knitty kitty replied to tiffanygosci's topic in Coping with Celiac Disease
      13

      New Celiac Mama in My 30s

      @tiffanygosci, Hello. I apologize for your thread being hijacked. I recognize your symptoms as being similar to what I experienced, the migraines, food and chemical sensitivities, hives, nausea, the numbness and tingling, joint pain, tummy problems, sleep problems, emotional lability, and the mom brain. My cycle returned early after I had my...
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,980
    • Most Online (within 30 mins)
      7,748
    Cathal Brugha
    Newest Member
    Cathal Brugha
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • SusanJ
      Celiac and dermatitis herpetiformis has taken Me from Me

      By SusanJ · Posted

      Two months ago, I started taking Dupixent for dermatitis herpetiformis and it has completely cleared it up. I can't believe it! I have had a terrible painful, intensely itchy rash for over a year despite going fully gluten-free. See if your doctor will prescribe Dupixent. It can be expensive but I am getting it free. When the dermatitis herpetiformis was bad I could not do anything. I just lay in bed covered in ice packs to ease the pain/itching and using way too Clobetasol. Dapsone is also very good for dermatitis herpetiformis (and it is generic). It helped me and the results were immediate but it gave me severe anemia so the Dupixent is better for me. Not sure if it works for everyone. I cannot help with the cause of your stress but from experience I am sure the severe stress is making the celiac and dermatitis herpetiformis worse. Very difficult for you with having children to care for and you being so sick. Would this man be willing to see a family therapist with you? He may be angry at you or imagine that your illness is a psychosomatic excuse not to take care of him. A therapist might help even if he won't go with you. Also do you have any family that you could move in with (with the kids) for a short time to get away? A break may be good for you both.
    • knitty kitty
      New Celiac Mama in My 30s

      By knitty kitty · Posted

      @tiffanygosci, Thiamine deficiency is a thing in pregnancy for "normal" people, so it's exponentially more important for those with celiac disease and malabsorption issues. I studied nutrition before earning a degree in Microbiology because I was curious what the vitamins were doing inside the body.  See my blog.  Click on my name to go to my page, scroll to drop down menu "activities" and select blog.   So glad you're motivated to see the dietician!  We're always happy to help with questions.  Keep us posted on your progress! 
    • tiffanygosci
      New Celiac Mama in My 30s

      By tiffanygosci · Posted

      Thank you for sharing all of this, Knitty Kitty! I did just want someone to share some commonality with. I did not know This one Deficiency was a thing and that it's common for Celiac Disease. It makes sense since this is a disorder that causes malabsorption. I will have to keep this in mind for my next appointments. You also just spurred me on to make that Dietician appointment. There's a lot of information online but I do need to see a professional. There is too much to juggle on my own with this condition.<3
    • RMJ
      Outgrow celiac?

      By RMJ · Posted

      I think your initial idea, eat gluten and be tested, was excellent. Now you have fear of that testing, but isn’t there also a fear each time you eat gluten that you’re injuring your body? Possibly affecting future fertility, bone health and more? Wouldn’t it be better to know for sure one way or the other? If you test negative, then you celebrate and get tested occasionally to make sure the tests don’t turn positive again. If you test positive, of course the recommendation from me and others is to stop gluten entirely.  But if you’re unable to convince yourself to do that, could a positive test at least convince you to minimize your gluten consumption?  Immune reactions are generally what is called dose response, the bigger the dose, the bigger the response (in this case, damage to your intestines and body). So while I am NOT saying you should eat any gluten with a positive test, the less the better.  
    • knitty kitty
      Outgrow celiac?

      By knitty kitty · Posted

      @Riley., Welcome to the forum, but don't do it!  Don't continue to eat gluten!  The health problems that will come if you continue to eat gluten are not worth it.  Problems may not show up for years, but the constant inflammation and nutritional losses will manifest eventually.  There's many of us oldsters on the forum who wish they'd been diagnosed as early.    Fertility problems, gallbladder removal, diabetes, osteoporosis and mental health challenges are future health issues you are toying with.   To dispel fear, learn more about what you are afraid of.  Be proactive.  Start or join a Celiac group in your area.  Learn about vitamins and nutrition.   Has your mother been checked for Celiac?  It's inherited.  She may be influencing you to eat gluten as a denial of her own symptoms.  Don't let friends and family sway you away from the gluten-free diet.  You know your path.  Stick to it.  Be brave. 
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.