Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Biopsy Results And Thyroid Please Help Me


MinxyMandy

Recommended Posts

MinxyMandy Apprentice

HI ya...

Right got my thyroid results and it says TSH : 0.68 the range is between 0.27 - 4.2 so does that mean its normal or low??

Also got results for bisopy but nmot seen doctor yet and it says:

D2 Biopsy

Maroscopic : two pale mucosal fragments 1- 2 mm

Microscopic reveals mucosa of normal villous patten. No evidence or active inflammation or organsims is seen?????

What now!!!!!!!!!!!!!!!

Does that mean I am not celiac??? I am at my last straw now

Mandx


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



ravenwoodglass Mentor
HI ya...

Right got my thyroid results and it says TSH : 0.68 the range is between 0.27 - 4.2 so does that mean its normal or low??

Also got results for bisopy but nmot seen doctor yet and it says:

D2 Biopsy

Maroscopic : two pale mucosal fragments 1- 2 mm

Microscopic reveals mucosa of normal villous patten. No evidence or active inflammation or organsims is seen?????

What now!!!!!!!!!!!!!!!

Does that mean I am not celiac??? I am at my last straw now

Mandx

Do not judge whether you need to be gluten free off of just the biopsy. You have 22 ft of small intestine and it is easy to miss damage. Also it may take years for gluten to damage your intestines enough to show up. In this time a lot of damage can be done to your brain and other body organs.

Judge whether you need to be gluten-free from your response to the diet and your challenge. Your thyroid looks to be in low normal levels, after a time gluten-free this may improve. The antibody response attacks more than just the gut it can also effect hormone levels and glands.

Nancym Enthusiast

When TSH goes low it is telling the thyroid to pump out less hormone. So a really, really low TSH might mean your thyroid is overactive. TSH going high says "I need more power, Scotty!" which would mean your pituitary gland is trying to signal the thyroid to give you more thyroid hormone.

So if your TSH goes too low it could mean you're HYPERthyroid, i.e. producing too much. If it goes too high it means you're HYPOthyroid, not producing enough thryoid hormone.

nora-n Rookie

About the TSH, normal TSH is quite close to 1. Yours is actually quite normal,even it is a tiny bit below 1.

About the biopsy, maybe you should ask for someone else to review the slides, as they usually comment on the height of the villi and neutrophils in the villi. Maybe teh comment about inflammation meant there were none. But the sandard is to count how many neurtophils there are per 100 cells. This was not done. I wonder if the pathologist was familiar with celiac biopsies. And, there still are pathologists out there who deny celiac unless the villi are totally gone. This was before.

super-sally888 Contributor

Hi,

Your TSH is within normal range. However, to be sure, they should also test FT3 and FT4 and test for thyroid antibodies. TSH is not a standalone indicator that your thyroid is ok. A doctor should palpate your thyroid to check for nodules or enlargement, and also should consider symptoms. Maybe you can tell us some more about why you suspect a thryoid problem.

Regarding biopsy. From what you wrote, it would appear to be normal. A positive biopsy can confirm the presence of celiac disease, but a negative one does not rule it out. (ie. no false positives, but there are false negatives). So just because your tests are negative doesn't mean all is normal and you don't have celiac.

Did they do blood testing for celiac? If not, they should. But again positive means you havce it, negative doesn't mean you don't (can still be intollerant to gluten).

Again, tell us some more about why you suspect celiac.

The best (and most important) way to confirm celiac is dietary response. However, diet doesn't earn money for drug companies and doesn't require special medical intervention (I am being cynical now!). Therefore, I would think that your next best move is to trial a gluten free diet (may take some practice) and see how you feel.

Best wishes

Sally

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      132,201
    • Most Online (within 30 mins)
      7,748

    Judy Wysocki
    Newest Member
    Judy Wysocki
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • trents
      NCGS does not cause damage to the small bowel villi so, if indeed you were not skimping on gluten when you had the antibody blood testing done, it is likely you have celiac disease.
    • Scott Adams
      I will assume you did the gluten challenge properly and were eating a lot of gluten daily for 6-8 weeks before your test, but if not, that could be the issue. You can still have celiac disease with negative blood test results, although it's not as common:  Clinical and genetic profile of patients with seronegative coeliac disease: the natural history and response to gluten-free diet: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606118/  Seronegative Celiac Disease - A Challenging Case: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441776/  Enteropathies with villous atrophy but negative coeliac serology in adults: current issues: https://pubmed.ncbi.nlm.nih.gov/34764141/  Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.
    • Xravith
      I'm very confused... My blood test came out negative, I checked all antibodies. I suppose my Total IgA levels are normal (132 mg/dl), so the test should be reliable. Still, I'm not relieved as I can't tolerate even a single biscuit. I need to talk to my doctor about whether a duodenal biopsy is necessary. But it is really possible to have intestinal damage despite having a seronegative results? I have really strong symptoms, and I don't want to keep skipping university lectures or being bedridden at home.
    • Scott Adams
      They may want to also eliminate other possible causes for your symptoms/issues and are doing additional tests.  Here is info about blood tests for celiac disease--if positive an endoscopy where biopsies of your intestinal villi are taken to confirm is the typical follow up.    
    • Scott Adams
      In the Europe the new protocol for making a celiac disease diagnosis in children is if their tTg-IgA (tissue transglutaminase IgA) levels are 10 times or above the positive level for celiac disease--and you are above that level. According to the latest research, if the blood test results are at certain high levels that range between 5-10 times the reference range for a positive celiac disease diagnosis, it may not be necessary to confirm the results using an endoscopy/biopsy: Blood Test Alone Can Diagnose Celiac Disease in Most Children and Adults TGA-IgA at or Above Five Times Normal Limit in Kids Indicates Celiac Disease in Nearly All Cases No More Biopsies to Diagnose Celiac Disease in Children! May I ask why you've had so many past tTg-IgA tests done, and many of them seem to have been done 3 times during short time intervals?    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.