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Canadian Karen

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This idiot on the other forum needs a lecture in biology. Explain this to her:

Most diseases (including Celiac) are NOT "genetic". Yes, you need to have the genes for them, but there are also TRIGGER(S) in the environment that are needed for the disease to develop. Many people have the genes for diseases they never develop.

Now, I do not think ALL autism cases are linked with autoimmunity, the leaky gut, etc. There are probably multiple causes. But I DO believe that a percentage are. And those cases very likely would improve on a gluten/casein free diet. Perhaps this women is pissed off because she tried the Gluten-free Casein-free diet and had no results. The diet unfortunately likely won't work for autism cases that are NOT linked to autoimmunity/the leaky gut. Maybe she is bitter? I do not want to get into a debate over the causes of autism, because there is not enough information to say one way or another. I think some will be helped by the diet (a good portion), some will not. And this seems to be the case.

Regardless, here is a way to break the biology of disease pathology down for this "enlightened" women:

*Genetic Diseases*

-Cystic Fibrosis

-Sickle Cell Anemia

-Down's Syndrome

-Turner Syndrome, etc.

Most diseases need BOTH genetics and a trigger to develop. Thus, if we could isolate/manipulate the triggers, we could impact the disease process and/or outcome.

1.) Autoimmune diseases are thought to be triggered by something in the environment like a virus, etc. So, the onset of Type 1 (insulin dependent or juvenile diabetes) diabetes may look like this:

Genes for Type 1 diabetes---> Lack of vitamin D exposure (a immune modulator) and lack of Omega 3 fatty acid encourage an environment for the disease to develop--->exposure to the triggering virus....the disease appears. The jury is out as to if exposure to gluten/casein/other food protein is additional factor.

2.) Asmtha requires the genes for the disease, and is often triggered by allergens and pollutants in the enviroment.

3.) Type 2 diabetes (the common form NOT related to Celiac) is a great model of gene and environment interaction. Yes, there are genes associated with the disease. But the disease *usually* does not express itself unless:

-A person has become obese/overweight

-Eats an unhealthy diet (excess fatty meats, bad fats, junk and processed foods, soda, simple carbs, excess carbs, etc.)

-Does not exercise

These are the top known triggers for Type 2 diabetes. Type 2 diabetes is not an autoimmune disease, but it is still triggered by the environment. Granted, there are about 10% of cases that are linked to hormonal disorders, certain medications like steroids, genetic defects that do not require a trigger, etc. But the vast majority of Type 2 diabetes cases are preventable if a person eats right, exercises, and maintains a normal weight. So *right there* is a case where genes can be fairly easily modified to prevent a disease. Or, HELP a disease that has already appeared. All of the above can help keep a Type 2 diabetic *off of medication and keep their blood sugar levels in good control*. So this is an example of genes being over-ridden by the environment, specifically diet.

I have not seen any evidence to suggest a Gluten-free Casein-free diet is "harmful", unless the child is not getting enough nutrients or is only being fed premade Gluten-free Casein-free "junk" foods.


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Canadian Karen Community Regular

That would be perfect! I did post about the trigger aspect, but not nearly as good as your explanation!

Unfortunately, they won't accept my posts anymore, my screen just freezes. Sheesh! Just because I had the gall to challenge their close-minded attitude, the kick me off! Oh well, my bad! :lol:

Glutenfreefamily Enthusiast
That would be perfect! I did post about the trigger aspect, but not nearly as good as your explanation!

Unfortunately, they won't accept my posts anymore, my screen just freezes. Sheesh! Just because I had the gall to challenge their close-minded attitude, the kick me off! Oh well, my bad! :lol:

Karen dont worry about it, you put the seed in their mind about the diet. Hopefully the parents might open their minds a little and think about trying it.

I feel bad for the kids, moms and dads that are too lazy to try and help them out is how I see it. They want to try meds first with multiple side effects instead of trying a more natural route <_<

Judyin Philly Enthusiast

:( so sorry Karen

At least you tired.

Judy

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    • trents
      Thanks for the thoughtful reply and links, Wheatwacked. Definitely some food for thought. However, I would point out that your linked articles refer to gliadin in human breast milk, not cow's milk. And although it might seem reasonable to conclude it would work the same way in cows, that is not necessarily the case. Studies seem to indicate otherwise. Studies also indicate the amount of gliadin in human breast milk is miniscule and unlikely to cause reactions:  https://www.glutenfreewatchdog.org/news/gluten-peptides-in-human-breast-milk-implications-for-cows-milk/ I would also point out that Dr. Peter Osborne's doctorate is in chiropractic medicine, though he also has studied and, I believe, holds some sort of certifications in nutritional science. To put it plainly, he is considered by many qualified medical and nutritional professionals to be on the fringe of quackery. But he has a dedicated and rabid following, nonetheless.
    • Scott Adams
      I'd be very cautious about accepting these claims without robust evidence. The hypothesis requires a chain of biologically unlikely events: Gluten/gliadin survives the cow's rumen and entire digestive system intact. It is then absorbed whole into the cow's bloodstream. It bypasses the cow's immune system and liver. It is then secreted, still intact and immunogenic, into the milk. The cow's digestive system is designed to break down proteins, not transfer them whole into milk. This is not a recognized pathway in veterinary science. The provided backup shifts from cow's milk to human breastmilk, which is a classic bait-and-switch. While the transfer of food proteins in human breastmilk is a valid area of study, it doesn't validate the initial claim about commercial dairy. The use of a Dr. Osborne video is a major red flag. His entire platform is based on the idea that all grains are toxic, a view that far exceeds the established science on Celiac Disease and non-celiac gluten sensitivity. Extraordinary claims require extraordinary evidence, and a YouTube video from a known ideological source is not that evidence."  
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