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Positive Iga, Negative Igg

renee28

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renee28 Rookie
renee28
Posted

Hi there,

Our three year old son came back with a 38 ttg iga (with anything above a 9 as positive) and a negative ttg igg which confuses me a bit.

We asked the doc to run a series of tests on our son because he had stomach flu like syptoms for a two week stretch, then constipation, then a three week stretch of the stomach flu.

Now he seems fine...did any of you present like this? Any thoughts on the neg. igg? We see the GI specialist Monday. Any specific questions I should ask?

Thank you!

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happygirl Collaborator
happygirl
Posted

The various Celiac tests do not have a 100% correlation, which is why there isn't one "perfect" test, but the tTG IgA is a pretty specific/sensitive test. You may want to discuss a follow up endoscopy with biopsy.

renee28 Rookie
renee28
Posted
  • Author
Hi there,

Our three year old son came back with a 38 ttg iga (with anything above a 9 as positive) and a negative ttg igg which confuses me a bit.

We asked the doc to run a series of tests on our son because he had stomach flu like syptoms for a two week stretch, then constipation, then a three week stretch of the stomach flu.

Now he seems fine...did any of you present like this? Any thoughts on the neg. igg? We see the GI specialist Monday. Any specific questions I should ask?

Thank you!

can anyone throw me a bone here????

  • 1 month later...
CDFAMILY Rookie
CDFAMILY
Posted

Hi Renee,

Sorry this is a little late,but I did want to comment on the negative IGG. I am a gold star celiac and have always had a very negative IGG in everything. I believe I may be IGG deficient as my daughter is. I discussed testing for IGG deficiency with my doctor but decided the only benefit of knowing would be to do IVIG treatments which I would not want to do. Instead I have my doctor check a lot of different areas for vitamin deficiencies and try to supplement to keep me healthy.

2 of my 3 children had high TTG/IGA and all were diagnosed with Celiac. My third did not have positive TTG's and is the one that is IGG and IMG deficent and a challange sent her into a major iron, ferritin, saturation deficiency with all Celiac symptoms returning so she was also dx with Celiac and DH.

I am sure I had Celiac all my life which caused many symptoms throughout childhood. The same is true for my children so I hope you consider the gluten free diet to prevent any unwanted health issues. I would also suggest you get all family members checked as they could also have silent Celiac Disease.

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    • SamAlvi
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      Thank you for the clarification and for taking the time to explain the terminology so clearly. I really appreciate your insight, especially the distinction between celiac disease and NCGS and how anemia can point more toward celiac. This was very helpful for me.
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