Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Tissue Transglutaminase Test Results

jackietran

Recommended Posts

jackietran Newbie
jackietran
Posted

Hi everyone,

My Tissue Transglutaminase IGG and IGA results came back tonight and it came back negative:

TISSUE TRANSGLUTAMINASE IGG 0.39 <0.90-Index

TISSUE TRANSGLUTAMINASE IGA 048 <0.90-Index

I have been having the typical symptoms of Celiac Disease, but wasn't sure if it was from a medication for my diabetes. My doctor ordered for these tests to be done after 9 months of being on the medication and having constant diarrhea (up to 3-4 times a day), stomach making noses, painful cramps, nausea, vomiting, etc. The medication's side effects was only diarrhea and that should have subsided in 3-4 months after being put on it as my body got used to it. However, even previous to being on this medication, I always had problems with food and my stomach, but never thought too much into it.

Since I have been off the medication 1 1/2 weeks ago and am still eating some type of gluten each day (since I heard you should stay on a gluten diet in case a biopsy needs to be done), I have not had diarrhea or stomach cramps until TODAY. And, it was strange to me, that I ate a pastry and was immediately knocked out and slept for 1 1/2 hours during the day. This hasn't happened since I've been off the medication and stopped eating huge amounts of gluten at once.

Anyways, I was comparing others' negative result values with mine. I'm noticing that many had lower IGG and IGA results than mine. For example, an IGG result of 0.11 and IGA of 0.21. Both of my results are higher than the ones that I've compared with online. Does this make any difference even though mine and another's are less than the standard range of <.90 (as made by Kaiser)? As in, does my higher results mean that I may have a higher possibility of being gluten intolerant vs someone who has lower results? Or does it not matter since it's lower than the standard range.

I apologize if these questions may sound like I'm crazy. I'm not looking to be diagnosed with this (who does?), but I'd just like to have an answer to why I may be having these symptoms. It would make me feel better just knowing that I may have some sensitivity to gluten, but not be officially diagnosed with celiac disease..and not just be clueless!

Thanks!

Jackie

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


ravenwoodglass Mentor
ravenwoodglass
Posted

Did your doctor run the antigliadin tests also or just the TTG?

jackietran Newbie
jackietran
Posted
  • Author

Did your doctor run the antigliadin tests also or just the TTG?

Just the TTG. I've written to her to let her know that my symptoms have come back, but am waiting for her response. I am hoping that she will run other tests rather than my initiating it, but I will if necessary.

ravenwoodglass Mentor
ravenwoodglass
Posted

Just the TTG. I've written to her to let her know that my symptoms have come back, but am waiting for her response. I am hoping that she will run other tests rather than my initiating it, but I will if necessary.

After you are done with all testing do give the diet a try as false negatives are not uncommon.

Skylark Collaborator
Skylark
Posted

Anyways, I was comparing others' negative result values with mine. I'm noticing that many had lower IGG and IGA results than mine. For example, an IGG result of 0.11 and IGA of 0.21. Both of my results are higher than the ones that I've compared with online. Does this make any difference even though mine and another's are less than the standard range of <.90 (as made by Kaiser)? As in, does my higher results mean that I may have a higher possibility of being gluten intolerant vs someone who has lower results? Or does it not matter since it's lower than the standard range.

Everything below the standard range is noise. The standard range is not zero because there is always some random background noise in this kind of assay. You also can't compare your numbers to anyone else because labs have different ways to score the assay. You're comparing apples to oranges.

It's really good you don't have TTG. Autoimmunity is no fun. You'll just have to pay attention to your body and how you feel after you eat gluten.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      129,914
    • Most Online (within 30 mins)
      7,748
    Andreaheath
    Newest Member
    Andreaheath
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • knitty kitty
      Waiting on biopsy after positive bloodwork, but also not really believing this is real

      By knitty kitty · Posted

      @Alibu, Migraines ran in my family as well.  Correcting my Thiamine insufficiency made a dramatic improvement in frequency and duration.   If you take Thiamine, B12 and B6 together, they have analgesic (pain relieving) properties.  Taking thiamine every day has cut down on their occurrence and severity for me.   Take Thiamine in the form Benfotiamine or TTFD (tetrahydrofurfuryl disulfide).  These forms get into the brain easily.  Magnesium Threonate gets into the brain easily, too, and helps thiamine work.  My gave a sigh of relief when I first took it, and no migraines. Yes, lowering histamine levels helps one feel better, too.  Vitamin C and B12 help reduce histamine.  A low histamine diet can help, too.  DAO supplements lower histamine, as well.  DOA is a digestive enzyme we can run short on.  
    • knitty kitty
      Refractory Celiac disease - what to do

      By knitty kitty · Posted

      @ehb   Great you're going to start the AIP diet!  I know it's scary and stressful, but you'll soon start feeling better.  It's a challenge, but you can make it.  Do ask for a Erythrocyte Transketolace test which tests for Thiamine level.   I hope your Vitamin D level is between 70 and 100 nmol/L.  In this optimal range, Vitamin D can act like a hormone and regulate the immune system.  Vitamin D 3 is the form that the body can utilize well.  I was prescribed the synthetic firm D2 and my body didn't like it.  I know getting my Vitamin D up in the eighties made a world of difference to me.  My depression improved and I felt so much better at higher levels.   I prefer Life Extension brand for many vitamins.  The important thing is to read the label and watch out for fillers like rice flour.  This may help. Keep us posted on your progress!  
    • ehb
      Refractory Celiac disease - what to do

      By ehb · Posted

      @knitty kitty I have an appointment to go over the results tomorrow. Vitamin D was in the normal range. I’ve decided to start the gluten contamination elimination diet, while avoiding nightshades as recommended by the AIP. I am still hoping to get support from a nutritionist or advice from the doctor about supplements to make sure I’m getting enough nutrients. I’m still having a hard time sorting through all of the different brands and possible combinations
    • cristiana
      confirmed via biopsy, quite depressed

      By cristiana · Posted

      We've definitely all had such thoughts.  But as Scott says, it does get easier with time.  I'm not sure where you are posting from but in England where I live, over the last ten years or so most things I missed at first now have gluten free substitutes.   I still miss Twix bars, and chocolate Penguins (a type of biscuit) but I'm hoping sooner or later someone will create a decent substitute for them! One thing that I remember my husband said to me when I was feeling down one day  was: "Why don't you try to think of all the things you can still eat, rather than the things you can't?"  The list is long, and it did help - sort of!  
    • Scott Adams
      Quaker Instant Grits, gluten-free?

      By Scott Adams · Posted

      It looks like they are naturally gluten-free, but not labeled gluten-free. https://www.quakeroats.com/products/hot-cereals/grits/instant-grits-plain
×
×
  • Create New...