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Tissue Transglutaminase Test Results

jackietran

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jackietran Newbie
jackietran
Posted

Hi everyone,

My Tissue Transglutaminase IGG and IGA results came back tonight and it came back negative:

TISSUE TRANSGLUTAMINASE IGG 0.39 <0.90-Index

TISSUE TRANSGLUTAMINASE IGA 048 <0.90-Index

I have been having the typical symptoms of Celiac Disease, but wasn't sure if it was from a medication for my diabetes. My doctor ordered for these tests to be done after 9 months of being on the medication and having constant diarrhea (up to 3-4 times a day), stomach making noses, painful cramps, nausea, vomiting, etc. The medication's side effects was only diarrhea and that should have subsided in 3-4 months after being put on it as my body got used to it. However, even previous to being on this medication, I always had problems with food and my stomach, but never thought too much into it.

Since I have been off the medication 1 1/2 weeks ago and am still eating some type of gluten each day (since I heard you should stay on a gluten diet in case a biopsy needs to be done), I have not had diarrhea or stomach cramps until TODAY. And, it was strange to me, that I ate a pastry and was immediately knocked out and slept for 1 1/2 hours during the day. This hasn't happened since I've been off the medication and stopped eating huge amounts of gluten at once.

Anyways, I was comparing others' negative result values with mine. I'm noticing that many had lower IGG and IGA results than mine. For example, an IGG result of 0.11 and IGA of 0.21. Both of my results are higher than the ones that I've compared with online. Does this make any difference even though mine and another's are less than the standard range of <.90 (as made by Kaiser)? As in, does my higher results mean that I may have a higher possibility of being gluten intolerant vs someone who has lower results? Or does it not matter since it's lower than the standard range.

I apologize if these questions may sound like I'm crazy. I'm not looking to be diagnosed with this (who does?), but I'd just like to have an answer to why I may be having these symptoms. It would make me feel better just knowing that I may have some sensitivity to gluten, but not be officially diagnosed with celiac disease..and not just be clueless!

Thanks!

Jackie

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ravenwoodglass Mentor
ravenwoodglass
Posted

Did your doctor run the antigliadin tests also or just the TTG?

jackietran Newbie
jackietran
Posted
  • Author

Did your doctor run the antigliadin tests also or just the TTG?

Just the TTG. I've written to her to let her know that my symptoms have come back, but am waiting for her response. I am hoping that she will run other tests rather than my initiating it, but I will if necessary.

ravenwoodglass Mentor
ravenwoodglass
Posted

Just the TTG. I've written to her to let her know that my symptoms have come back, but am waiting for her response. I am hoping that she will run other tests rather than my initiating it, but I will if necessary.

After you are done with all testing do give the diet a try as false negatives are not uncommon.

Skylark Collaborator
Skylark
Posted

Anyways, I was comparing others' negative result values with mine. I'm noticing that many had lower IGG and IGA results than mine. For example, an IGG result of 0.11 and IGA of 0.21. Both of my results are higher than the ones that I've compared with online. Does this make any difference even though mine and another's are less than the standard range of <.90 (as made by Kaiser)? As in, does my higher results mean that I may have a higher possibility of being gluten intolerant vs someone who has lower results? Or does it not matter since it's lower than the standard range.

Everything below the standard range is noise. The standard range is not zero because there is always some random background noise in this kind of assay. You also can't compare your numbers to anyone else because labs have different ways to score the assay. You're comparing apples to oranges.

It's really good you don't have TTG. Autoimmunity is no fun. You'll just have to pay attention to your body and how you feel after you eat gluten.

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