Childrens "negative" Blood Test Results

[nothungry]

I had my children, ages 5 and 8 tested after I was diagnosed with celiac disease. The only one of the tests that came back positive was the "Antigliadin Abs, IgG". My 8 year old had 51 and my 5 year old had 97. My gastroenterologist and pediatrician said that overall they test negative even though these results are high positive. What does the IgG indicate? Why do they test for it if it is not an indicator of celiac disease? Is tTG really the only thing I have to be concerned about?

[KaitiUSA]

Well the full panel really will show some insight. Every test kind of has its piece to the puzzle. IgG and IgA are used to pick up gluten antibodies and a problem with gluten in the body. This is usually the first indication of celiac.

tTG and EMA are used more to detect damage in the intestines-these are the best 2 tests and pretty accurate.Then there is the total serum IgA which is used to rule out IgA deficiency. If they are IgA deficient then that can be why IgA came back negative.

If just the IgG comes back positive with all the testing it may be in beginning stages and not being picked up or even other possibilities.

The IgG is the least accurate test out of all of the tests and that alone positive would most likely not result in a diagnosis.

If symptoms are there though and it is in the family then there is a likely chance that they are in beginning stages.

[cdford]

Even though both my boys are symptomatic (one significantly so), their tests came back negative. I strongly suspect that will change over time.