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Celiac Or Not?

Jbadeo

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Jbadeo Newbie
Jbadeo
Posted

Hi all. I posted before, but wanted a few more opinions in regards to my symptoms and blood test results. I have been having on going digestive symptoms such as constant nausea, diarrhea and loose stools, and just a general feeling of being unwell. I developed these symptoms over a year ago. Sometimes my symptoms come and go, lasting 4 or 5 days, and other times I may only feel unwell 2 or 3 times a month.

Here is one blood test result below:

Component Your result Standard range Units

TISSUE TRANSGLUTAMINASE IgG 0.89 < 0.90 - Index

Tissue transglutaminase IgA 1.53 < 0.90 - Index

Since these tests, my GI dr ordered a full celiac panel as well as a genetic blood test. My celiac panel results were all in the normal range, including my Ttg IgG and IgA (my IgA was positive above only a month prior). I would post my ranges for the full celiac panel, but unfortunately misplaced the paper. My genetic test determined I carry the DQ-8 gene, and signaled I have only a moderate probability of developing Celiac. I am twice as likely to develop it.

Just curious, I know Ttg IgA is not specific for Celiacs like some of the other tests found on the full celiac panel, but why did I have a high positive result (ruling out I probably don't have crones or any other diseases going)? And then why was the result negative only a month later on the full celiac panel? It's just confusing.

Have there been any other celaics on this board diagnosed as having celiac disease and only carry the DQ-8 gene?

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Skylark Collaborator
Skylark
Posted

You didn't stop eating gluten before the negative TTG test did you?

Roda Rising Star
Roda
Posted

If you had your tests run at different labs that is one possibility of the inconsistencies. A lot of the time different labs will have different reporting ranges. Also I would think the measure of things could varry to some degree. If the numbers are within a reasonable + or - range of the original, I would say it could be a testing varriation. Just a thought.

Jbadeo Newbie
Jbadeo
Posted
  • Author

You didn't stop eating gluten before the negative TTG test did you?

I was still eating gluten, although I was going through a phase with only sporadic symptoms (once or twice a week).

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      Contact them.
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