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Cyrex Cross Reactivity Test Accuracy?


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18 replies to this topic

#16 Foolish_Michie

 
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Posted 08 December 2013 - 10:32 AM

"We only embrace tests that have endured rigorous scientific evaluations. So far, these tests have received no evidence-based support."

 

http://www.curecelia...erolab-or-cyrex

 

 

"There is not yet reliable data about cross-reactivity. As for the alleged possibility that many gluten-free foods or drinks (such as coffee, milk, orange juice, etc.) would trigger symptoms in celiac individuals due to hidden antigens mimicking gluten or cross-reacting with anti-gluten antibodies, it must be clearly stated that this is all false information, devoid of any scientific basis, and must be rejected as untrue."

 

http://www.curecelia...ross-reactivity

 

I understand what you are saying and this is a controversial subject. The theory makes sense, however, and understanding it has helped me significantly. And it is important to note that not everyone with celiac reacts to foods other than the standard gluten ones. We probably see a higher percentage here because you have to be pretty desperate to spend a lot of time on a disease forum looking for answers.

 

Personally, I'm not interested in going the Cryex or Eurolab route and I have no idea how accurate the tests are. I don't need a lab test to tell me that my forbidden list includes corn, soy, rice and nightshades. And I certainly don't need to spend a small fortune to know that I have yet to find a 'gluten free' product on the shelf that didn't make me sick.

 

Anyway, beyond the accuracy of lab tests, the following info might prove useful for some. I still prefer the way it is explained by the link provided above.

http://www.scirp.org...x?paperID=26626

http://www.ncbi.nlm....pubmed/22298027

http://www.ncbi.nlm....v/pubmed/371884

http://gut.bmj.com/c...t/54/6/769.full

http://www.usbiotek....ticalReview.pdf

http://publications....e/chapter1.html


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#17 Foolish_Michie

 
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Posted 08 December 2013 - 10:39 AM

Also, if there were any truth to this, why aren't we ALL reacting to the same things?

 

Again, based on my understanding of the theory, it is entirely dependent on the specific antibodies your body has developed.

 

Honestly, read the link. It is fascinating.

 

I've taken too much space on this thread :( Sorry. I'll leave you all alone now.


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#18 biochemmama

 
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Posted 09 October 2014 - 06:07 AM

I determined that I had a problem with a number of the things from the cross reactivity panel before actually knowing about the test from Cyrex so had an aha moment when I found this out.  The Paleo Mom doesn't write anything that she cannot back up with science.  Cross reactivitydoes exist - otherwise there would not be any such thing as oral allergy syndrome!  I've found that if I eliminate my cross reactants for several months, I can reintroduce in small amounts so, it seems to me, that cross reactivity is concentration dcependent (concentration of my antibodies) which makes sense.  Finally, I cannot remember the exact number, but there are numerous epitopes (small chains of amino acids that the antibodies react to) to which celiacs can react.  I might have an antibody response to epitope 1 and 6 which cross react with coffee  while someone else might have and immune response to epitopes 2 and 9 which might cross react to amaranth or something else which explains why we all react to different things.  As for corn reactors, take a look at this paper http://www.ncbi.nlm....pubmed/24152750


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#19 kareng

 
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Posted 09 October 2014 - 07:25 AM

.  Cross reactivity does exist - otherwise there would not be any such thing as oral allergy syndrome!  I

 

 

Allergies are different than Celiac disease.  Currently there isn't evidence that there are other foods besides gluten that cause Celiac disease.

 

 

http://www.curecelia...ross-reactivity

 

"There is not yet reliable data about cross-reactivity. As for the alleged possibility that many gluten-free foods or drinks (such as coffee, milk, orange juice, etc.) would trigger symptoms in celiac individuals due to hidden antigens mimicking gluten or cross-reacting with anti-gluten antibodies, it must be clearly stated that this is all false information, devoid of any scientific basis, and must be rejected as untrue."


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