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Difference Between Celiac And Leaky Gut Syndrome?


JohanJohan

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JohanJohan Rookie

Whats the difference between celiac and leaky gut syndrome?

Celiac = strong intolerance to gluten + gluten gets into the body from a weak/broken stomach?

Leaky gut syndrome = weak/broken stomach + different food particles that werent suppose to get into the body but does so + Gluten being one of the more serious ones + Gluten being the food that most likely caused the leaky gut?


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mushroom Proficient

I have the following snippet in my notes about Dr. Alessio Fasano, who is a world-recognized authority in celiac. For some reason I do not have the citation for it.

"When we think about the intestine, most of us imagine a long tube from mouth to anus. What we don’t often think about is that the cells in the intestinal wall have doors or channels in between them. These doors can open and close. Dr. Fasano made the discovery that a molecule called zonulin is responsible for signaling the opening and closing of these doors in the intestine. When a person with celiac disease consumes gluten, a ton of zonulin gets produced, opening the doors in the intestine wall and allowing larger proteins such as gluten and other particles to enter the blood stream. The immune system in the blood stream becomes overwhelmed and creates an autoimmune response."

This is Dr. Fasano's theory on leaky gut - that it is controlled by zonulin. This is a very simplified version. :)

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    • trents
      You might consider asking for a referral to a RD (Registered Dietician) to help with food choices and planning a diet. Even apart from any gluten issues, you will likely find there are some foods you need to avoid because of the shorter bowel but you may also find that your system may make adjustments over time and that symptoms may improve.
    • Ello
      I wish Dr’s would have these discussions with their patients. So frustrating but will continue to do research. Absolutely love this website. I will post any updates on my testing and results.  Thank you
    • trents
      Losing 12" of your small bowel is going to present challenges for you in nutritional uptake because you are losing a significant amount of nutritional absorption surface area. You will need to focus on consuming foods that are nutritionally dense and also probably look at some good supplements. If indeed you are having issues with gluten you will need to educate yourself as to how gluten is hidden in the food supply. There's more to it than just avoiding the major sources of gluten like bread and pasta. It is hidden in so many things you would never expect to find it in like canned tomato soup and soy sauce just to name a few. It can be in pills and medications.  Also, your "yellow diarrhea, constipation and bloating" though these are classic signs of a gluten disorder, could also be related to the post surgical shorter length of your small bowel causing incomplete processing/digestion of food.
    • Ello
      Yes this information helps. I will continue to be pro active with this issues I am having. More testing to be done. Thank you so much for your response. 
    • trents
      There are two gluten-related disorders that share many of the same symptoms but differ in nature from each other. One is known as celiac disease or "gluten intolerance". By nature, it is an autoimmune disorder, meaning the ingestion of gluten triggers the body to attack it's own tissues, specifically the lining of the small bowel. This attack causes inflammation and produces antibodies that can be detected in the blood by specific tests like the TTG-IGA test you had. Over time, if gluten is not withheld, this inflammation can cause severe damage to the lining of the small bowel and even result in nutrient deficiency related health issues since the small bowel lining is organ where all the nutrition found in our food is absorbed.  The other is NCGS (Non Celiac Gluten Sensitivity or just "gluten sensitivity") which we know less about and are unsure of the exact mechanism of action. It is not an autoimmune disorder and unlike celiac disease it does not damage the lining of the small bowel, though, like celiac disease, it can cause GI distress and it can also do other kinds of damage to the body. It is thought to be more common than celiac disease. Currently, we cannot test for NCGS. Celiac disease must first be ruled out to arrive at a diagnosis of NCGS. Both disorders require elimination of gluten from the diet.  Either of these disorders can find their onset at any stage of life. We know that celiac disease has a genetic component but the genes are inactive until awakened by some stress event. About 40% of the general population has the genetic potential to develop celiac disease but only about 1% develop active celiac disease. The incidence of NCGS is thought to be considerably higher. I hope this helps.
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