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How Much Vitamin D Should Infants Get to Possibly Prevent Celiac Disease?
The Endocrine Society 92nd Annual Meeting
Celiac.com 06/24/2010 - I have previously suggested vitamin D deficiency and the makeup of gut bacteria during pregnancy and infancy, while breast-feeding and prior to and during the introduction of gluten, may be factors leading to the onset of celiac disease. The question of how much vitamin D should be given to infants remains open. The current recommendation, by the American Academy of Pediatrics, is that children of all ages should receive 400 IU of vitamin D each day. A recent limited study of 74 diabetic children, however, suggests that this recommended dose may still be insufficient for most children. The children were given daily vitamin D doses ranging from 400 IU to 2000 IU over a 12-month period and their vitamin D status was monitored. Most of the children remained vitamin D insufficient or deficient at the end of the study. The study concluded that all children younger than 5 years should probably receive at least 1000 IU of vitamin D daily. Further study is needed, especially with specific emphasis on the onset and prevention of celiac disease during infancy.
Medscape Medical News - June 22, 2010: More Evidence That Current Pediatric Vitamin D Recommendation is Often Inadequate
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Can Bifidobacterium infantis Natren Life Start Strain Help Active Celiac Disease?
To determine if the probiotic Bifidobacterium natren life start (NLS) strain might affect the treatment and clinical features of patients with untreated celiac disease, a team of researchers recently conducted an exploratory, randomized, double-blind, placebo-controlled study on the effects of Bifidobacterium infantis natren life start super strain in active celiac disease.... [READ MORE]
Secretory Immunoglobulin A, CD71, and Transglutaminase-2 Interactions Alter Permeability of Intestinal Epithelial Cells to Gliadin Peptides
In duodenal biopsy samples from people with active celiac disease, the transferrin receptor, CD71, is up-regulated, and promotes retro-transport of secretory immunoglobulin A (SIgA)-gliadin complexes.... [READ MORE]
Influence of HLA-DQ2 and DQ8 on Severity in Celiac Disease
A group of researchers recently studied the ways in which HLA-DQ2 and DQ8 might influence the severity of celiac disease.... [READ MORE]
Environmental Effects on the Human Microbiota as Possible Celiac Disease Trigger
Celiac disease is known to be triggered, at least in part, by environmental factors.... [READ MORE]
Roy S. Jamron holds a B.S. in Physics from the University of Michigan and an M.S. in Engineering Applied Science from the University of California at Davis, and independently investigates the latest research on celiac disease and related disorders.View all articles by Roy Jamron
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