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Study Shows Non-celiac Wheat Sensitivity is a Persistent Condition

Is non-celiac wheat sensitivity a persistent condition?


Photo: CC--Clare Black

Celiac.com 08/23/2017 - A team of researchers recently set out to assess how many patients with a diagnosis of non-celiac wheat sensitivity (NCWS) still experienced symptoms of wheat sensitivity after an average follow-up time of 99 months.

The research team included Antonio Carroccio, Alberto D’Alcamo, Giuseppe Iacono, Maurizio Soresi, Rosario Iacobucci, Andrea Arini, Girolamo Geraci, Francesca Fayer, Francesca Cavataio, Francesco La Blasca, Ada M. Florena, and Pasquale Mansueto.

Using data collected from 200 participants from a previous study of non-celiac wheat sensitivity, performed between July and December 2016 in Italy, the team found that 148 of these individuals still followed a strict wheat-free diet.

In total, 175 patients (88%) said that they had fewer symptoms after a diagnosis of non-celiac wheat sensitivity and general improvement.

Of the 148 patients who adhered strictly to a gluten-free diet, 145 (98%) had reduced symptoms, compared with 30 of 52 patients who did not adhere to a gluten-free diet (58%) (P < .0001).

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Of the 22 patients who repeated the double-blind, placebo-controlled challenge, 20 reacted to wheat.

The numbers and percentages of the 148 non-celiac wheat sensitivity patients on a strict wheat-free diet who reported that the following symptoms recurred after occasional and accidental wheat consumption: Lack of well-being 135 (91%); Tiredness 102 (69%); Foggy mind 68 (46%); Menstrual alterations 54 (36%); Anemia 46 (31%); Weight increase 45 (30%); Joint/muscle pain 35 (24%); Headache 31 (21%); Weight loss 30 (20%); Anxiety 18 (12%); Skin rash 16 (11%); Recurrent cystitis 12 (8%); Depression 10 (7%).

From these numbers, the team concludes that non-celiac wheat sensitivity is a persistent condition.

Clinicaltrials.gov registration number: NCT02823522.

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4 Responses:

 
Marlene
Rating: ratingfullratingfullratingfullratingemptyratingempty Unrated
said this on
28 Aug 2017 2:40:14 PM PST
I will never consider taking part in a double blind study! After spending most of my teen and adult years with painful swollen joints, terrible exhaustion and yes some intestinal problems, I went on the South Beach diet at 60 and the constant pain and fatigue went away. I had been diagnosed and treated for RA by different doctors with little relief until a rheumatologist at UM said some families had something - but good news no joint damage! 15 years later no wheat for me!

 
Keely
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
28 Aug 2017 8:22:59 PM PST
It's not "wheat" sensitivity because wheat basically doesn't exist anymore. What passes for wheat is a deformed GM version of it and I believe that's what causes the symptoms. It's like the Bizarro version of Superman.

 
admin
( Author)
said this on
29 Aug 2017 4:21:11 PM PST
This is a common misconception, but wheat in the USA is actually not genetically modified.

 
Jeff Adams
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated ( Author)
said this on
07 Sep 2017 3:08:03 PM PST
Please note that no commercial wheat is GMO. That is true globally. All strains of commercial wheat are hybrids. There has been some work to produce GMO strains of wheat for commercial markets, but as yet none is being grown or sold.




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