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Scott Adams

Mast Cells Tied to Onset and Progression of Celiac Disease

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Researchers understand pretty well that celiac disease is driven in part by an accumulation of immune cells in the duodenal mucosa as a consequence of both adaptive and innate immune responses to undigested gliadin peptides.

Mast cells are innate immune cells that produce a majority of co-stimulatory signals and inflammatory mediators in the intestinal mucosa. A team of researchers recently set out to evaluate the role of mast cells in the development of celiac disease.

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Scott Adams

Celiac.com - Celiac Disease Board Moderator

Founder Celiac.com

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