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Blood test looks normal, could it still be coeliac


Napqueen

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Napqueen Newbie

Hello, I have many symptoms of coeliac disease and went to my doctor on Monday to get tested. I get extreme fatigue, anxiety, occasional diarrhoea and abdominal cramps, dry skin/rash on my hands, bloating and nausea. I notice symptoms are worse after having a heavy gluten meal such as pasta or spaghetti.  

I've had some of my blood tests back online which seem normal. Erythrocyte sedimentation rate was 7mm/h and Anti-tissue transglutnase level was 0.5 u/mL. I think these results are normal but I feel like coeliac would explain all my symptoms.

Can you please confirm that these mean i dont have coeliac or is it still a possibility, would the doctor have run more tests which haven't come back yet and what do I do next? Thank you ?


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cyclinglady Grand Master
38 minutes ago, Napqueen said:

Hello, I have many symptoms of coeliac disease and went to my doctor on Monday to get tested. I get extreme fatigue, anxiety, occasional diarrhoea and abdominal cramps, dry skin/rash on my hands, bloating and nausea. I notice symptoms are worse after having a heavy gluten meal such as pasta or spaghetti.  

I've had some of my blood tests back online which seem normal. Erythrocyte sedimentation rate was 7mm/h and Anti-tissue transglutnase level was 0.5 u/mL. I think these results are normal but I feel like coeliac would explain all my symptoms.

Can you please confirm that these mean i dont have coeliac or is it still a possibility, would the doctor have run more tests which haven't come back yet and what do I do next? Thank you ?

Welcome!  You really need lab ranges, but I will take your word that the results were normal.  The Anti-TTG is the celiac test.  Did they run an Immunoglobulin A (IgA) test?  If that result is not normal, you could be IgA deficient and that tells the doctor that the Anti-TTG IgA test is not valid.  Add in the fact that 10% of celiacs are seronegative.  Consider asking for the complete celiac panel.  

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You can not rule out celiac disease based on this one result.  

The other simple test looks for inflammation that could be attributed any any autoimmune disease or illness like some cancers, etc.  

Napqueen Newbie
19 minutes ago, cyclinglady said:Welcome!  You really need lab ranges, but I will take your word that the results were normal.  The Anti-TTG is the celiac test.  Did they run an Immunoglobulin A (IgA) test?  If that result is not normal, you could be IgA deficient and that tells the doctor that the Anti-TTG IgA test is not valid.  Add in the fact that 10% of celiacs are seronegative.  Consider asking for the complete celiac panel.  

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You can not rule out celiac disease based on this one result.  

The other simple test looks for inflammation that could be attributed any any autoimmune disease or illness like some cancers, etc.  

Thank you for the reply. I’m not sure if they’ve done more tests they’ve been putting them up gradually so maybe there will be another one. The normal range for the Anti-tissue transglutnase was >10.9u/ml

 
 
cyclinglady Grand Master

I can tell you that I have never had a positive TTG  (either IgA or IgG versions).  My EMA has always been negative too, even in follow-up testing.  I have ONLY had a positive on the DGP IgA and my 8ntetinal biopsies revealed moderate to severe patches of intestinal damage.  I did not even have any GI symptoms!   Odd, but true.  The TTG catches most celiacs, but not all!  

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