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rohitrohit

Confusion about HLA-B27,Gluten,Vitamin B12 deficiency,Celiac

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I was having chronic itchy eye and eye inflammation problem and have visited to 4 different ophthalmologists. All have same answers, like you have allergy of something which is difficult to detect, gave prescription of steroid drops which was helping temporarily only and advised to wear goggles. This problem remained around 3-4 years.

Then during net surfing I came to know that I have symptoms of vitamin B12 deficiency which I have confirmed through lab test. I started taking pills and injections as advised by doctor.

The good news was that along with B12 deficiency symptoms itchy eye problem was solved.

Then I surfed on net and came to know that HLA-B27 positive people have gluten sensitivity and intake of gluten does not let intestine to absorb vitamin B12 and hence continuous intake of gluten creates vitamin B12 deficiency which lead to itchy eye problem and B12 deficiency related problems.

I again visited ophthalmologist to know about HLA-B27 but he did not agree that vitamin B12 deficiency can create eye problem.

I have celiac disease related symptom like chronic fatigue but that is also related to vitamin B12 deficiency.

I am confused what problem my body has

 

My mother has chronic diarrhea and headache problem since 2005 which seems celiac disease. Through net I have surfed she might be also having gluten sensitivity and we have conducted food allergy panel test for ascertaining gluten allergy but test is negative for wheat but positive for peanut and sesame.

Now I realized that wheat allergy is different from gluten allergy and have wasted money in allergy panel test.

 

Now i am confused about what should be forward path

Kindly read my case and help me diagnose problem

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You and your mother should get celiac testing done. Any doctor can order a Celiac panel and if positive would refer you to a GI doctor for an endoscopy. Don't stop eating gluten until all celiac related testing is done.  After all testing is done you should both go on the diet strictly no matter what the results. Some folks don't show up positive on testing but can still have a serious problem with gluten.

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Yesterday I consulted GI doctor for my mother.Her TGT IGA test result is negative.Doctor has advised for endoscopy.

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Good to hear that despite the negative TTG, the Doctor ordered an endoscopy.  Keep in mind that not every diagnosed celiac has ever tested positive on the TTG.  I personally only get a positive on the DGP, even in follow-up testing.  I hope you and your mother are able to find answers to both your issues.  

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