Severe COVID-19 Is Fueled by Disrupted Gut Barrier Integrity

[Posterboy]

To All,

I came across this research recently on COVID-19 and the gut-long axis and how COVID-19 might start as a Leaky Gut problem and wanted to share and see what other's thought.

The previous article I read on this topic.....indicated COVID-19 might start in the GUT and why many patients don't have respiratory problems until the 2nd week.

Here is the early article I read on it in early 2020

Entitled "Coronavirus can infect intestine as well as lungs, says study"

https://finance.yahoo.com/news/coronavirus-infect-intestine-well-lungs-093000721.html

IF the first week it finds into to the body through the ACE2 receptor then it makes sense that the GI tract would be infected first.

Here is the research entitled "Severe COVID-19 Is Fueled by Disrupted Gut Barrier Integrity"

https://www.medrxiv.org/content/10.1101/2020.11.13.20231209v1.full

And this recent research that bears out the Saliva in the mouth might harbor the Corona Virus and be a means for transmission.

See this research entitled "Scientists reveal salivary gland cells as sites of COVID-19 infection"

https://www.news-medical.net/news/20210325/Scientists-reveal-salivary-gland-cells-as-sites-of-COVID-19-infection.aspx

quoting from the News Medical article.

"They looked for individual cells that expressed two key entry proteins - ACE2 and the TMPRSS2 protease - which SARS-CoV-2 uses to infect human cells, and discovered that salivary gland ductal cells and some gingival, or gum, cells expressed both proteins. This showed that these cells were vulnerable to infection."

They also noted quoting again.

"Of the 27 people who experienced symptoms, those with virus in their saliva were more likely to report loss of taste and smell, suggesting that oral infection might underlie oral symptoms of COVID-19."

I quoted them together because they are related research.

I don't know what all it means....but it is interesting research anyway.

Here are the other recent articles on Celiac.com for others to read about Celiac disease and COVID-19 if you have not read them already.

Just so you won't have to go look them up.....I am including them here for those who have not read them yet....

Maybe you can make more sense of it than me.....but I think COVID-19 might just start as a "Leaky Gut" issue first then spread to the lungs???

What do others think?

I hope this is helpful but it is not medical advise.

Posterboy,

[Posterboy]

31 minutes ago, Posterboy said:

I came across this research recently on COVID-19 and the gut-long axis and how COVID-19 might start as a Leaky Gut problem and wanted to share and see what other's thought.

That was the Gut-Lung Axis.....sorry for the typo!

I did not see how to edit it....so I wanted you to be sure it was exploring how the gut-lung axis can be connected through the ACE2 receptor as I understand it.

Posterboy,

[Scott Adams]

This finding is definitely interesting and well hopefully lead to better treatments for COVID-19, and I’m glad to see that there is research which shows that people with celiac disease are at no higher risk for complications due to COVID-19.