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Questions about blood test results


Heifer

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Heifer Newbie

Hi . My name is Heather. I’m 34 years old. I’ve had stomach problems my whole life. I was tested for Celiac Disease my results were negative for the celiac comp panel testing but my Tragl IGG was a weak postive and I’m confused about what that means. My results were:        
      Tragl IGG 7 normal range under 6.               
       Tragl IGM 2.9 normal range less 9.6         
Tragl IGA 1.2 normal range less than 4 

They also tested  Immunoglobulins Blood Test my IGA was 66 normal range is 70-400 . Does that mean it’s too low? I’m just confused I have colonoscopy and endoscopy scheduled for next week. Thank you . 
   


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trents Grand Master

Low IGA levels can give negative results for the tTG test. The IGA related tests are the ones used to diagnose celiac disease. The tTG-IGA test is the test is the most specific test for celiac disease but it is the least sensitive. The others in the "full" celiac IGA panel are more sensitive but less specific.

This might help: https://celiac.org/about-celiac-disease/screening-and-diagnosis/screening/

A full celiac blood work panel would include the "other tests" mentioned in the article. Unfortunately, many general practitioners are not very knowledgeable about celiac diagnosis. The endoscopy/biopsy you will have next week will look for damaged "villi" in the small bowel lining. (Note: the colonoscopy checks the lower or large bowel for other problems). The two hallmarks of Celiac disease are a skin rash called dermatitis herpetiformis and damaged SB villi. Celiacs can have one or the other or both.

Scott Adams Grand Master

This article has more info, even though it's rather old:

 

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