How likely with these results will celiac be the diagnosis?

[GlitterPants8]

My daughter hasn't been growing so we've done a bunch of tests. Her Dr was concerned about her results and is referring us to a gastroenterologist. How likely would you say her being diagnosed celiac is? I'm guessing it's likely. 

Ttg-iga 153.4 (standard range  <15 u/ml) 

Ttg- igg 61 (same range) 

 

 

[trents]

Extremely likely. That Ttg-IGA is quite high and that test is considered to be the centerpiece of antibody testing for celiac disease.

[GlitterPants8]

1 hour ago, trents said:

Extremely likely. That Ttg-IGA is quite high and that test is considered to be the centerpiece of antibody testing for celiac disease.

Thanks. We were looking for growth hormone issues so we were a little surprised that it might be celiac. 

I carry 2 copies of DQ8 so I was tested a few years ago but it was negative. I never really thought my kids might have it. 

[trents]

There is a 44% chance that a first degree relative of someone with celiac disease will develop celiac disease. If you had some triggering stress event such as a viral infection, you could still develop celiac disease yourself. With both genes the guns are loaded.

[Scott Adams]

In the UK presently they are diagnosing celiac disease if a blood test results is 10x the threshold level for celiac disease, which you have here in the first result that you shared. A biopsy may not be required in your case, but definitely discuss this with your doctor, and don't go gluten-free until all tests are completed.

[GlitterPants8]

3 hours ago, Scott Adams said:

In the UK presently they are diagnosing celiac disease if a blood test results is 10x the threshold level for celiac disease, which you have here in the first result that you shared. A biopsy may not be required in your case, but definitely discuss this with your doctor, and don't go gluten-free until all tests are completed.

I'm hoping they don't want to do a biopsy. She will likely need to be put under for them to do it. Just getting enough blood for the tests was really upsetting for her. 

[DebJ14]

On 8/31/2021 at 6:26 PM, GlitterPants8 said:

My daughter hasn't been growing so we've done a bunch of tests. Her Dr was concerned about her results and is referring us to a gastroenterologist. How likely would you say her being diagnosed celiac is? I'm guessing it's likely. 

Ttg-iga 153.4 (standard range  <15 u/ml) 

Ttg- igg 61 (same range) 

 

 

I just came across this post.  My daughter in law has both DQ2 and DQ8 genes and my son (her husband) has one copy of the DQ2 gene Their oldest son was born full term weighing just under 5 pounds.  At one he was 18 pounds and at 2 he was just 19 pounds.  Doctors discussed failure to thrive.  When both my son and daughter in law were diagonosed with Celiac their doctor said they should take the kids gluten free too with a genetic profile like that.  He said we treat other diseases preventatively, especially to stop genetic expression, and it was his opinion that celiac should be treated the same way.  When their tiny, emaciated looking child, was put on a gluten free diet he gained 6 pounds and grew almost 2 inches in one month.  Now at age 17 he is right in the middle of the pack regarding his height and weight.