So confused about bloodwork!

[debbrewer58]

I was diagnosed with celiac disease by bloodwork and biopsy. My IgG 10.32 and IgA 181. However the IgM was 0.11.

Now l'm going for a ct with doppler of the liver ( diagnosed a few years ago for fatty liver.) I'm getting anxious

because no-one is explaining this to me. Anyone else have experienced this?

[trents]

Welcome to the forum, debbrewer58!

Deb, almost missed the actual text of your post. There is a huge gap of blank at the beginning and I had to scroll way down to see what you actually posted.

Can you repost your entire celiac lab values including reference ranges for negative vs. positive. Different labs used different reference ranges so the test result number doesn't mean much without knowing the reference range. Also, I am not familiar with IgM. Is that a typo? You only have a limited time to edit any post so you will probably have to repost.

The IGA of 181 simply means your "total serum IgA" is within normal range. They check that because low total IGA can skew the individual celiac antibody scores downward. Did they check the tTG-IGA? That is the most common celiac antibody test ordered by physicians as it combines good sensitivity with good specificity.

Liver inflammation is not uncommonly associated with celiac disease. About 18% of celiacs experience elevated liver enzymes. In fact, that's what led to my own diagnosis of celiac disease about 20 years ago. Within a few months of going gluten free the inflammation subsided and the enzymes dropped into normal range.

 

Edited July 7, 2022 by trents

[Scott Adams]

Welcome to the forum!

Hopefully going on a gluten-free diet will help your liver issues, as research has shown that a gluten-free diet can help normalize liver problems in celiacs. This category has many research articles on this topic:

https://www.celiac.com/celiac-disease/celiac-disease-amp-related-diseases-and-disorders/liver-disease-and-celiac-disease/