Gluten-free Hydroxychloroquine

[movietime]

Is there a Hydroxychloroquine that is both gluten-free and vegetarian? I know that Quinoric by Bristol Labs is, but I don’t know it’s available in the US. Every pharmacy I’ve called doesn’t carry it.

[knitty kitty]

@movietime

Hydroxychloroquine is one of many pharmaceuticals that shuts down thiamine transporters on cell surfaces, thus causing a functional thiamine deficiency despite normal blood levels of thiamine.  

Thiamine, Vitamin C and steroids have been used to help Covid patients.  

This study finds that thiamine and pyridoxine can bind to the "docking station" where the spike of Covid binds, thus preventing the virus from entering cells.  

Modeling studies on the role of vitamins B1 (thiamin), B3 (nicotinamide), B6 (pyridoxamine), and caffeine as potential leads for the drug design against COVID-19

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640828/

Since thiamine and pyridoxine are safe, they show potential to replace Hydroxychloroquine and its harmful side effects.

[movietime]

Thank you, but the hydroxychloroquine is to modulate my overactive immune system. I’m having a severe autoimmune reaction when exposed to manufactured citric acid fumes when people are heating foods containing this preservative. Manufactured citric acid is produced using aspergillus black mold. I have one of the multi-susceptibility genes, 14-5-52B. This started a little over a year after eliminating gluten. Apparently, there’s a connection, although it’s rare. I’ve read about similar outcomes and was in touch with someone with the same condition. I already take B vitamins and drink green tea.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097542/

 

[knitty kitty]

I haven't heard of that, but I'm familiar with thiamine's beneficial effects on mycotoxin production.

Have you read this article?  

Effects of thiamine on growth, aflatoxin production, and aflr gene expression in A.parasiticus

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490319/

Quoting the conclusion in part...

"Based on the obtained results, thiamine could not inhibit the fungal growth completely. However, the rate of afIR gene expression and aflatoxin production was significantly reduced after fungal treating with thiamine."

 

I take high dose Thiamine as per Dr. Lonsdale (see link below) and I've noticed that I'm not as reactive to mold in the environment.  

I've learned that in thiamine insufficiency different HLA genes are more likely to switch on.  It has to do with mitochondrial dysfunction.

Here's an article from Dr. Lonsdale and Dr. Marrs'  website...

https://www.hormonesmatter.com/tag/mold-exposure/

[movietime]

I just read it. Thank you for sending. What dosage and brand name of B1 do you take?

[knitty kitty]

I take Allithiamine, Benfotiamine, and Thiamine Hydrochloride.  

Ecological Formulas, Life Extension, and Thiamax are some brand names although there are others.  

Benefits from Thiamine Hydrochloride can be seen at 500-2000 mg.  Allithiamine and Benfotiamine are fat soluble (they get into cells easily) and benefits can be seen at lower doses of 100mg or more.  

It's a matter of starting with a lower dose and increasing until you feel improvement.  Keep increasing doses slowly as long as you keep feeling improvement.  If you start feeling worse back down on the dose.  

I take all three throughout the day.  I continue to take a combination of all these about every three hours or with meals.  

If you experience insomnia, don't take these as close to bedtime.

Be sure to take some magnesium citrate or magnesium glycinate as magnesium is needed to make certain enzymes with Thiamine.  Also a good B Complex, because the eight essential B vitamins need each other to work properly.  

Hope this helps!

[Scott Adams]

If you know the manufacturer you can see its ingredients here:

https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Hydroxychloroquine 

[movietime]

On 1/20/2023 at 1:50 PM, Scott Adams said:

If you know the manufacturer you can see its ingredients here:

https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Hydroxychloroquine 

Thank you for this!

[movietime]

On 1/11/2023 at 11:34 AM, knitty kitty said:

I take Allithiamine, Benfotiamine, and Thiamine Hydrochloride.  

Ecological Formulas, Life Extension, and Thiamax are some brand names although there are others.  

Benefits from Thiamine Hydrochloride can be seen at 500-2000 mg.  Allithiamine and Benfotiamine are fat soluble (they get into cells easily) and benefits can be seen at lower doses of 100mg or more.  

It's a matter of starting with a lower dose and increasing until you feel improvement.  Keep increasing doses slowly as long as you keep feeling improvement.  If you start feeling worse back down on the dose.  

I take all three throughout the day.  I continue to take a combination of all these about every three hours or with meals.  

If you experience insomnia, don't take these as close to bedtime.

Be sure to take some magnesium citrate or magnesium glycinate as magnesium is needed to make certain enzymes with Thiamine.  Also a good B Complex, because the eight essential B vitamins need each other to work properly.  

Hope this helps!

Thank you! I’ve been taking Life Extension BioActive Complete B-Complex which contains 100mg of Thiamine, which I guess is not nearly enough. I’ll have to increase the dosage. I decided against the Hydroxychloroquine after learning more about the potential retinal damage.

[Wheatwacked]

The best way to quiet your autoimmune system is by raising your vitamin D level.

 

Quote

Vitamin D and the Immune System   Vitamin D can modulate the innate and adaptive immune responses. Deficiency in vitamin D is associated with increased autoimmunity as well as an increased susceptibility to infection.

   Mayo Clinic Proceedings: Vitamin D Is Not as Toxic as Was Once Thought   Ekwaru et al recently reported on more than 17,000 healthy adult volunteers participating in a preventative health program and taking varying doses of vitamin D up to 20,000 IU/d. These patients did not demonstrate any toxicity, and the blood level of 25(OH)D in those taking even 20,000 IU/d was less than 100 ng/mL.

Edited January 25, 2023 by Wheatwacked
typo

[movietime]

Thank you. I take 5000 mgs. I’ll trying increasing the dose. I’m having severe neurological, gastrointestinal symptoms, along with muscle pain and more recently muscle spasticity when exposed to manufactured citric acid fumes (a preservative that’s produced using aspergillus mold). This started about a year after eliminating gluten and has gotten progressively worse. The only time I had sustained relief from symptoms was when Urgent Care put me on Levofloxacin. I didn’t know it had the potential to be a dangerous drug, but it brought me tremendous relief. I’m trying to find a similar drug with the same kind of immunomodulating  properties.

[Wheatwacked]

Antibiotics kill off both the good and bad gut bacteria indescriminately. Fermented foods help replenish and nourish the good. Homemade fermented dill pickles. Lately I've been drinking a ounce of the pickle juice and it has helped foot cramps. Could also be salt deficient if you are eating low salt diet. Salt tablets were used on hot sweaty days. Multiple deficiencies are common so try one if it helps continue and try the next for the remaining symptoms. 

5 hours ago, movietime said:

neurological, gastrointestinal symptoms

Especially gall bladder type symptoms like yellow, floaty stools bloat, brain fog. Not enough choline in your diet can cause this, also. Choline is the basis for acetyl choline (nerve transmission, and bile (fat digestion) among other essential functions and most people consume below the RDA

• Choline Deficiency Symptoms & Signs
• low energy levels of fatigue.
• memory loss.
• cognitive decline.
• learning disabilities.
• muscle aches.
• nerve damage.
• mood changes or disorders.
• Feeling anxious or restless
• Fatty liver, otherwise known as non-alcoholic fatty liver disease (NAFLD)
• Muscle damage
• Hyperhomocysteinemia
• Produce and repair DNA
• Detox
• Regulate histamine
• Support eye health
• Fuel your cells
• High-dose choline reduced DNA damage in men with methylation problems.
• About 9 in 10 to 19 in 20 pregnant women don't meet the AI for choline.