Blood Work and Endoscopy Today

[Adthomas]

My bloodwork came back high positive for celiac back in July. I've been eating gluten ever since to prepare for my endoscopy which was today. They said everything LOOKED good. Has anyone had a normal LOOKING endoscopy but biopsy results came back with celiacs? 

[Scott Adams]

This scenario, unfortunately, is fairly common. 

It only takes one positive blood test result to mean that you may have celiac disease, and although a negative biopsy may technically rule this out for now, it could still mean that you've simply caught this early, before it has caused you to have damaged villi. 

It's doubtful that the GI doctor would catch minor damage to the villi without a microscopic examination, and it is unclear if they did this yet, as it usually takes days or longer go get the biopsy results.

It is also possible that your GI doctor did not take enough biopsy specimens, or perhaps took them in areas where you show no damage. Did they give you a Marsh score for those biopsies? 

[RMJ]

Some endoscopes that doctors use to look at tissue during the endoscopy have better magnification than others. So sometimes damage can be seen (with good magnification) and sometimes it can’t.

I won’t hope that you have celiac disease, but I hope you get a clear cut diagnosis!