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DQA1*05 gene

Hawk4
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Go to solution Solved by Scott Adams,

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Hawk4 Rookie
Hawk4
Posted

Hello.

Previously, TTG-IGA was 17x or more of upper range of normal.  Now:

positive for HLA-DQ2 and DQA1*05

negative for HLA-DQ8.

So one of the genes that is generally present in celiac is there.  But does anyone know the significance of DQA1*05?

Thanks!

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  • Solution
Scott Adams Grand Master
Scott Adams
Posted
  • Solution

The presence of the HLA-DQA1*05 allele, also known as DQ2.5, is associated with an increased risk of developing celiac disease. However, it's important to note that having the allele does not guarantee the development of the disease.

This article has some info:

 

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