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Brain Related Celiac


Nancym

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Nancym Enthusiast
Dr. Hadjivassiliou and colleagues recently published a report of nine patients with gluten ataxia compared with seven patients with ataxia due to other causes. They found tissue transglutaminase IgA deposition on jejunum intestinal tissue on all nine patients with gluten ataxia but none of the control patients. Brain tissue from an autopsy of one patient with gluten ataxia was also found to have IgA tTG deposits in the cerebellum, pons and medulla of the brain but not in a control brain.

Previous studies have found negative blood celiac blood tests in patients with gluten ataxia suggesting that they may not have celiac though they had gluten related disease. In light of a new report that blood test negative celiac disease can have intestinal tTG and advanced intestinal damage it is curious to wonder if the gluten ataxia patients with blood tests negative are seronegative celiac disease. It is increasingly appearing that there is a very broad spectrum of gluten related disease and there are non-celiac gluten related symptoms that include the brain, skin, musculoskeletal system as well as the gut.

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Viola 1 Rookie

Very Interesting, thanks for posting that :)

happygirl Collaborator

Nancy,

Thank you for sharing!

Laura

jerseyangel Proficient

Thanks Nancy--I want to copy that and send it to my mom.

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