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Gluten & Casein Reactions


CMCM

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CMCM Rising Star

I just read something interesting on an allergy site where I was researching casein related things:

Here's the whole thing, which may be of interest to everyone:

Allergic reactions to casein and/or whey protein are caused by an immunological sensitivity to milk protein - rather than the sugar. A reaction to casein or whey can cause breathing problems, hives and rashes, abdominal pain, and possibly serious weight loss. While there are at least 30 types of potentially allergy-causing proteins in milk, casein is the most prevalent. The proteins lactalbumin and lactoglobulin, which comprise the whey proteins, are also known to cause problems.

Because whey proteins are changed by high heat, those sensitive to whey can sometimes tolerate evaporated, boiled, or sterilized milk and milk powder. That other 80% of milk, the casein, is unfortunately for sensitive folks, heat stable. It's also the most common allergen in cheese, which seems to be particularly craved by those who can't have it. The harder the cheese, the more casein it contains.

And because milk proteins are not altered sufficiently when milk is converted to other dairy products like cheese or yogurt, the only way to avoid reactions is to avoid milk in all its forms.

Interestingly, too, the molecular structure of casein is similar to that of gluten, and those with celiac disease may also suffer from casein intolerance.


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HawkFire Explorer

Avoid Dairy... GREAT IDEA! Notmilk.com has good info. I hope the anti dairy movement picks up speed and catches on sooner rather than later.

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    • Scott Adams
      This is a very common question, and the most important thing to know is that no, Guinness is not considered safe for individuals with coeliac disease. While it's fascinating to hear anecdotes from other coeliacs who can drink it without immediate issues, this is a risky exception rather than the rule. The core issue is that Guinness is brewed from barley, which contains gluten, and the standard brewing process does not remove the gluten protein to a level safe for coeliacs (below 20ppm). For someone like you who experiences dermatitis herpetiformis, the reaction is particularly significant. DH is triggered by gluten ingestion, even without immediate gastrointestinal symptoms. So, while you may not feel an instant stomach upset, drinking a gluten-containing beer like Guinness could very well provoke a flare-up of your skin condition days later. It would be a gamble with a potentially uncomfortable and long-lasting consequence. Fortunately, there are excellent, certified gluten-free stouts available now that can provide a safe and satisfying alternative without the risk.
    • MogwaiStripe
      Interestingly, this thought occurred to me last night. I did find that there are studies investigating whether vitamin D deficiency can actually trigger celiac disease.  Source: National Institutes of Health https://pmc.ncbi.nlm.nih.gov/articles/PMC7231074/ 
    • Butch68
      Before being diagnosed coeliac I used to love Guinness. Being made from barley it should be something a coeliac shouldn’t drink. But taking to another coeliac and they can drink it with no ill effects and have heard of others who can drink it too.  is this everyone’s experience?  Can I drink it?  I get dermatitis herpetiformis and don’t get instant reactions to gluten so can’t try it to see for myself. 
    • trents
      NCGS does not cause damage to the small bowel villi so, if indeed you were not skimping on gluten when you had the antibody blood testing done, it is likely you have celiac disease.
    • Scott Adams
      I will assume you did the gluten challenge properly and were eating a lot of gluten daily for 6-8 weeks before your test, but if not, that could be the issue. You can still have celiac disease with negative blood test results, although it's not as common:  Clinical and genetic profile of patients with seronegative coeliac disease: the natural history and response to gluten-free diet: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606118/  Seronegative Celiac Disease - A Challenging Case: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441776/  Enteropathies with villous atrophy but negative coeliac serology in adults: current issues: https://pubmed.ncbi.nlm.nih.gov/34764141/  Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.
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